Modulating insulin signaling and trafficking at the blood-brain barrier endothelium using lipid based nanoemulsions.

Wang, Lushan; Wiedmann, Timothy S; Kandimalla, Karunya K

Wang, Lushan; Wiedmann, Timothy S; Kandimalla, Karunya K.

Afiliação

Wang L; Department of Pharmaceutics, University of Minnesota, College of Pharmacy, Minneapolis, MN 55455, United States; Brain Barriers Research Center, University of Minnesota, College of Pharmacy, Minneapolis, MN 55455, United States.
Wiedmann TS; Department of Pharmaceutics, University of Minnesota, College of Pharmacy, Minneapolis, MN 55455, United States.
Kandimalla KK; Department of Pharmaceutics, University of Minnesota, College of Pharmacy, Minneapolis, MN 55455, United States; Brain Barriers Research Center, University of Minnesota, College of Pharmacy, Minneapolis, MN 55455, United States. Electronic address: kkandima@umn.edu.

Int J Pharm ; 622: 121823, 2022 Jun 25.

Article em En | MEDLINE | ID: mdl-35605891

Assuntos

Barreira Hematoencefálica; Insulina; Barreira Hematoencefálica/metabolismo; Endotélio/química; Endotélio/metabolismo; Ácidos Graxos Insaturados; Humanos; Insulina/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Óleo de Soja

Palavras-chave

Insulin resistance; Insulin signaling; Insulin trafficking; Lipid rafts; Nanoemulsions; Olive oil; Soybean oil; Unsaturated fatty acids

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article