LIM Kinases, Promising but Reluctant Therapeutic Targets: Chemistry and Preclinical Validation In Vivo.

Berabez, Rayan; Routier, Sylvain; Bénédetti, Hélène; Plé, Karen; Vallée, Béatrice

Berabez, Rayan; Routier, Sylvain; Bénédetti, Hélène; Plé, Karen; Vallée, Béatrice.

Afiliação

Berabez R; Institut de Chimie Organique et Analytique, University of Orléans, CNRS UMR 7311, CEDEX 2, 45067 Orléans, France.
Routier S; Institut de Chimie Organique et Analytique, University of Orléans, CNRS UMR 7311, CEDEX 2, 45067 Orléans, France.
Bénédetti H; Centre de Biophysique Moléculaire, UPR 4301, CNRS, University of Orléans and INSERM, CEDEX 2, 45071 Orléans, France.
Plé K; Institut de Chimie Organique et Analytique, University of Orléans, CNRS UMR 7311, CEDEX 2, 45067 Orléans, France.
Vallée B; Centre de Biophysique Moléculaire, UPR 4301, CNRS, University of Orléans and INSERM, CEDEX 2, 45071 Orléans, France.

Cells ; 11(13)2022 06 30.

Article em En | MEDLINE | ID: mdl-35805176

Assuntos

Actinas; Quinases Lim; Citoesqueleto de Actina/metabolismo; Fatores de Despolimerização de Actina/metabolismo; Actinas/metabolismo; Citoesqueleto/metabolismo; Humanos; Quinases Lim/metabolismo

Palavras-chave

LIMK; in vivo preclinical validation; medicinal chemistry

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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