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Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain.
Chi, Gamma; Liang, Qiansheng; Sridhar, Akshay; Cowgill, John B; Sader, Kasim; Radjainia, Mazdak; Qian, Pu; Castro-Hartmann, Pablo; Venkaya, Shayla; Singh, Nanki Kaur; McKinley, Gavin; Fernandez-Cid, Alejandra; Mukhopadhyay, Shubhashish M M; Burgess-Brown, Nicola A; Delemotte, Lucie; Covarrubias, Manuel; Dürr, Katharina L.
Afiliação
  • Chi G; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Liang Q; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Sridhar A; Department of Neuroscience and Vickie and Jack Farber Institute for Neuroscience, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, 19107, UK.
  • Cowgill JB; Department of Applied Physics, Science for Life Laboratory, KTH, Solna, Sweden.
  • Sader K; Department of Applied Physics, Science for Life Laboratory, KTH, Solna, Sweden.
  • Radjainia M; Materials and Structural Analysis, Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG, Eindhoven, Netherlands.
  • Qian P; Materials and Structural Analysis, Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG, Eindhoven, Netherlands.
  • Castro-Hartmann P; Materials and Structural Analysis, Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG, Eindhoven, Netherlands.
  • Venkaya S; Materials and Structural Analysis, Thermo Fisher Scientific, Achtseweg Noord 5, 5651 GG, Eindhoven, Netherlands.
  • Singh NK; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • McKinley G; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Fernandez-Cid A; Exscientia Ltd., The Schrödinger Building, Heatley Road, The Oxford Science Park, Oxford, OX4 4GE, UK.
  • Mukhopadhyay SMM; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Burgess-Brown NA; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Delemotte L; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Covarrubias M; Structural Genomics Consortium, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
  • Dürr KL; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford, OX3 7DQ, UK.
Nat Commun ; 13(1): 4087, 2022 07 15.
Article em En | MEDLINE | ID: mdl-35840580
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article