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Disruption of tubulin-alpha4a polyglutamylation prevents aggregation of hyper-phosphorylated tau and microglia activation in mice.
Hausrat, Torben Johann; Janiesch, Philipp C; Breiden, Petra; Lutz, David; Hoffmeister-Ullerich, Sabine; Hermans-Borgmeyer, Irm; Failla, Antonio Virgilio; Kneussel, Matthias.
Afiliação
  • Hausrat TJ; Department of Molecular Neurogenetics, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251, Hamburg, Germany. torben.hausrat@zmnh.uni-hamburg.de.
  • Janiesch PC; Department of Molecular Neurogenetics, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251, Hamburg, Germany.
  • Breiden P; Department of Molecular Neurogenetics, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251, Hamburg, Germany.
  • Lutz D; Department of Structural Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251, Hamburg, Germany.
  • Hoffmeister-Ullerich S; Department of Neuroanatomy and Molecular Brain Research, Ruhr University Bochum, 44801, Bochum, Germany.
  • Hermans-Borgmeyer I; Bioanalytics Facility, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251, Hamburg, Germany.
  • Failla AV; Transgenic Animal Unit, Center for Molecular Neurobiology, ZMNH, University Medical Center Hamburg-Eppendorf, Falkenried 94, 20251, Hamburg, Germany.
  • Kneussel M; Microscopy Imaging Facility, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Germany.
Nat Commun ; 13(1): 4192, 2022 07 20.
Article em En | MEDLINE | ID: mdl-35858909
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article