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Two new thymol derivatives from Eupatorium fortunei.
Shi, Jing; Dai, Yan-Peng; Yuan, Min; Sun, Xiao-Man; Song, Chuan-Jie; Liu, Yu-Guo.
Afiliação
  • Shi J; Department of Pharmaceutics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
  • Dai YP; Shandong Academy of Traditional Chinese Medicine, Jinan, China.
  • Yuan M; Shandong Academy of Traditional Chinese Medicine, Jinan, China.
  • Sun XM; Department of Pharmaceutics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
  • Song CJ; Department of Pharmaceutics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
  • Liu YG; Department of Pharmaceutics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Nat Prod Res ; : 1-7, 2022 Sep 29.
Article em En | MEDLINE | ID: mdl-36175160
Two new thymol derivatives (1-2) were isolated from the aerial parts of Eupatorium fortunei. Their structures were elucidated on the basis of comprehensive spectroscopic data analysis as 8,9-dehydrothymol-3-O-ß-glucoside (1), and 9-(acetyloxy)thymol-3-yl (3-methylbut-2-enoate) (2). All isolates were evaluated for cytotoxic activities with IC50 values greater than 50 µM in vitro against MCF-7, HeLa, A549, and Hep G-2 cancer cells.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article