Spata2L Suppresses TLR4 Signaling by Promoting CYLD-Mediated Deubiquitination of TRAF6 and TAK1.

Zhang, Zhenzhen; Zhang, Shuangyan; Jiang, Xiaoli; Wu, Dandan; Du, Yaning; Yang, Xiao-Dong

Zhang, Zhenzhen; Zhang, Shuangyan; Jiang, Xiaoli; Wu, Dandan; Du, Yaning; Yang, Xiao-Dong.

Afiliação

Zhang Z; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Zhang S; Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Jiang X; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Wu D; Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Du Y; Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
Yang XD; Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

Biochemistry (Mosc) ; 87(9): 957-964, 2022 Sep.

Article em En | MEDLINE | ID: mdl-36180997

Assuntos

Fator 6 Associado a Receptor de TNF; Receptor 4 Toll-Like; Citocinas/metabolismo; Enzima Desubiquitinante CYLD/genética; Enzima Desubiquitinante CYLD/metabolismo; Lipopolissacarídeos/farmacologia; NF-kappa B/metabolismo; Poliubiquitina/metabolismo; Fator 6 Associado a Receptor de TNF/genética; Fator 6 Associado a Receptor de TNF/metabolismo; Receptor 4 Toll-Like/metabolismo

Palavras-chave

CYLD; Spata2; Spata2L; TLR4; deubiquitination; inflammation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2022 Tipo de documento: Article