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Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease.
Song, Jia; Yang, Rui-Rui; Chang, Jie; Liu, Ya-Dan; Lu, Cheng-Hao; Chen, Li-Fan; Guo, Hao; Zhang, Ying-Hui; Fan, Zi-Sheng; Zhou, Jing-Yi; Zhou, Gui-Zhen; Zhang, Ke-Ke; Luo, Xiao-Min; Chen, Kai-Xian; Jiang, Hua-Liang; Zhang, Su-Lin; Zheng, Ming-Yue.
Afiliação
  • Song J; The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, China.
  • Yang RR; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Chang J; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Liu YD; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Lu CH; Shanghai Institute for Advanced Immunochemical Studies, and School of Life Science and Technology, Shanghai Tech University, Shanghai, 200031, China.
  • Chen LF; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Guo H; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
  • Zhang YH; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
  • Fan ZS; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhou JY; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Zhou GZ; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhang KK; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Luo XM; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Chen KX; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Jiang HL; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
  • Zhang SL; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
  • Zheng MY; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China.
Acta Pharmacol Sin ; 44(4): 791-800, 2023 Apr.
Article em En | MEDLINE | ID: mdl-36229599

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article