Simulating toxicokinetic variability to identify susceptible and highly exposed populations.

Breen, Miyuki; Wambaugh, John F; Bernstein, Amanda; Sfeir, Mark; Ring, Caroline L

Breen, Miyuki; Wambaugh, John F; Bernstein, Amanda; Sfeir, Mark; Ring, Caroline L.

Afiliação

Breen M; Center for Computational Toxicology and Exposure, US Environmental Protection Agency, Research Triangle Park, NC, USA.
Wambaugh JF; Center for Computational Toxicology and Exposure, US Environmental Protection Agency, Research Triangle Park, NC, USA.
Bernstein A; Oak Ridge Institute for Science and Education (ORISE) fellow at the Center for Public Health and Environmental Assessment, Research Triangle Park, NC, USA.
Sfeir M; Oak Ridge Institute for Science and Education (ORISE) fellow at the Center for Computational Toxicology and Exposure, Research Triangle Park, NC, USA.
Ring CL; Center for Computational Toxicology and Exposure, US Environmental Protection Agency, Research Triangle Park, NC, USA. Ring.Caroline@epa.gov.

J Expo Sci Environ Epidemiol ; 32(6): 855-863, 2022 11.

Article em En | MEDLINE | ID: mdl-36329211

Assuntos

Inquéritos Nutricionais; Estados Unidos; Humanos; United States Environmental Protection Agency

Palavras-chave

Environmental justice; Generic physiologically-based toxicokinetic (PBTK) models; Model variability and uncertainty; Modeling software tools; New approach methodologies (NAMs); Population simulator

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans País/Região como assunto: America do norte Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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