Adenovirus-mediated SIRT1 protects cochlear strial marginal cells in a D-gal-induced senescent model in vitro.

Zhao, Chunli; Yang, Zijing; Gong, Shusheng; Du, Zhengde

Zhao, Chunli; Yang, Zijing; Gong, Shusheng; Du, Zhengde.

Afiliação

Zhao C; Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong'an Road, Xicheng District, Beijing, 100050, China.
Yang Z; Clinical Center for Hearing Loss, Capital Medical University, Beijing, 100050, China.
Gong S; Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, No. 95, Yong'an Road, Xicheng District, Beijing, 100050, China.
Du Z; Clinical Center for Hearing Loss, Capital Medical University, Beijing, 100050, China.

Mol Biol Rep ; 50(1): 541-551, 2023 Jan.

Article em En | MEDLINE | ID: mdl-36350417

Assuntos

Presbiacusia; Camundongos; Animais; Presbiacusia/genética; Presbiacusia/metabolismo; Presbiacusia/patologia; Sirtuína 1/genética; Sirtuína 1/metabolismo; Galactose; Adenoviridae/genética; Adenoviridae/metabolismo; Camundongos Endogâmicos C57BL; Envelhecimento/genética; Estresse Oxidativo; DNA Mitocondrial/genética

Palavras-chave

Age-related hearing loss; D-GALACTOSE; Inner ear; Oxidative stress; Strial marginal cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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