Inhibition of Synaptic Glutamate Exocytosis and Prevention of Glutamate Neurotoxicity by Eupatilin from <i>Artemisia argyi</i> in the Rat Cortex.

Lu, Cheng-Wei; Wu, Chia-Chan; Chiu, Kuan-Ming; Lee, Ming-Yi; Lin, Tzu-Yu; Wang, Su-Jane

Inhibition of Synaptic Glutamate Exocytosis and Prevention of Glutamate Neurotoxicity by Eupatilin from Artemisia argyi in the Rat Cortex.

Lu, Cheng-Wei; Wu, Chia-Chan; Chiu, Kuan-Ming; Lee, Ming-Yi; Lin, Tzu-Yu; Wang, Su-Jane.

Afiliação

Lu CW; Department of Anesthesiology, Far-Eastern Memorial Hospital, New Taipei City 22060, Taiwan.
Wu CC; Department of Mechanical Engineering, Yuan Ze University, Taoyuan 32003, Taiwan.
Chiu KM; Department of Anesthesiology, Far-Eastern Memorial Hospital, New Taipei City 22060, Taiwan.
Lee MY; Division of Cardiovascular Surgery, Cardiovascular Center, Far-Eastern Memorial Hospital, New Taipei City 22060, Taiwan.
Lin TY; Department of Electrical Engineering, Yuan Ze University, Taoyuan 32003, Taiwan.
Wang SJ; Department of Medical Research, Far-Eastern Memorial Hospital, New Taipei City 22060, Taiwan.

Int J Mol Sci ; 23(21)2022 Nov 02.

Article em En | MEDLINE | ID: mdl-36362193

Assuntos

Artemisia; Síndromes Neurotóxicas; Ratos; Animais; Ácido Glutâmico/metabolismo; Sinapsinas/metabolismo; Artemisia/metabolismo; 4-Aminopiridina/farmacologia; Ratos Sprague-Dawley; Córtex Cerebral/metabolismo; Cálcio/metabolismo; Sinaptossomos/metabolismo; Exocitose; Ácido Caínico/farmacologia; Síndromes Neurotóxicas/metabolismo

Palavras-chave

cortex; eupatilin; glutamate excitotoxicity; glutamate release; neuroprotection; synaptosome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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