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Insight into Potential Biomedical Application of Mesoporous Materials.
Spiridon, Irene Alexandra; Cӑruntu, Irina Draga; Spiridon, Iuliana; Brӑescu, Radu.
Afiliação
  • Spiridon IA; Department of Morpho-Functional Sciences I-Pathology 1, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
  • Cӑruntu ID; Department of Morphofunctional Sciences I-Histology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
  • Spiridon I; "Petru Poni" Institute of Macromolecular Chemistry, Aleea Gr. Ghica Vodӑ 41A, 700487 Iasi, Romania.
  • Brӑescu R; Department of Implantology, Removable Prosthesis, Denture Technology, "Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Pharmaceutics ; 14(11)2022 Nov 04.
Article em En | MEDLINE | ID: mdl-36365200
The physicochemical properties of many drugs have a decisive impact on their bioavailability, as well as the pharmacokinetic efficiency in various disease therapeutics. That is why mesoporous materials have attracted a special interest in the drug delivery field, facilitating the loading of drugs into their pores due to their high surface area and porosity. The interfacial interactions established with drug molecules represent the driving force for efficient drug loading and controlled release kinetics. Moreover, these materials offer an optimal design for implantable local-delivery devices or for improving the accuracy of imaging techniques in clinical diagnosis. Their use is validated by improvements in therapeutic outcome and prevention of side effects. This review discusses the role of mesoporous materials in different biomedical applications.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2022 Tipo de documento: Article