Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines.

Halberstadt, Adam L; Luethi, Dino; Hoener, Marius C; Trachsel, Daniel; Brandt, Simon D; Liechti, Matthias E

Halberstadt, Adam L; Luethi, Dino; Hoener, Marius C; Trachsel, Daniel; Brandt, Simon D; Liechti, Matthias E.

Afiliação

Halberstadt AL; Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, 92093-0804, USA. ahalberstadt@ucsd.edu.
Luethi D; Research Service, VA San Diego Healthcare System, San Diego, CA, USA. ahalberstadt@ucsd.edu.
Hoener MC; Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Pharmaceutical Sciences, University Hospital Basel and University of Basel, Basel, Switzerland.
Trachsel D; pRED, Roche Innovation Center Basel, Neuroscience Research, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Brandt SD; ReseaChem GmbH, Burgdorf, Switzerland.
Liechti ME; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK.

Psychopharmacology (Berl) ; 240(1): 115-126, 2023 Jan.

Article em En | MEDLINE | ID: mdl-36477925

Assuntos

Alucinógenos; Camundongos; Masculino; Humanos; Animais; Alucinógenos/farmacologia; Alucinógenos/química; Receptor 5-HT2A de Serotonina; Inteligência Artificial; Serotonina; Camundongos Endogâmicos C57BL; Relação Estrutura-Atividade

Palavras-chave

5-HT2A receptor; Hallucinogen; Head-twitch response; Mice; Phenethylamine; Psychedelic

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google