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ALDH2 deficiency increases susceptibility to binge alcohol-induced gut leakiness, endotoxemia, and acute liver injury in mice through the gut-liver axis.
Rungratanawanich, Wiramon; Lin, Yuhong; Wang, Xin; Kawamoto, Toshihiro; Chidambaram, Saravana Babu; Song, Byoung-Joon.
Afiliação
  • Rungratanawanich W; Section of Molecular Pharmacology and Toxicology, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, 9000 Rockville Pike, Bethesda, MD, 20892, USA. Electronic address: wiramon.rungratanawanich@nih.gov.
  • Lin Y; Laboratory of Liver Diseases, National Institute on Alcohol Abuse and Alcoholism, 9000 Rockville Pike, Bethesda, MD, 20892, USA. Electronic address: yulin@mail.nih.gov.
  • Wang X; Department of Neurosurgery, Brigham and Women's Hospital, Harvard University Medical School, Boston, MA, 02115, USA. Electronic address: xwang@rics.bwh.harvard.edu.
  • Kawamoto T; Occupational Health Research and Development Center, Japan Industrial Safety and Health Association, Tokyo, Japan. Electronic address: t-kawamoto@jisha.or.jp.
  • Chidambaram SB; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Mysuru, 570015, KA, India; Centre for Experimental Pharmacology and Toxicology (CPT), JSS Academy of Higher Education & Research, Mysuru, 570015, KA, India. Electronic address: saravanababu.c@jss
  • Song BJ; Section of Molecular Pharmacology and Toxicology, Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, 9000 Rockville Pike, Bethesda, MD, 20892, USA. Electronic address: bj.song@nih.gov.
Redox Biol ; 59: 102577, 2023 02.
Article em En | MEDLINE | ID: mdl-36528936
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article