Thymoquinone Suppresses Angiogenesis in DEN-Induced Hepatocellular Carcinoma by Targeting miR-1-3p.

Tadros, Samer A; Attia, Yasmin M; Maurice, Nadine W; Fahim, Sally A; Abdelwahed, Fatma M; Ibrahim, Samar; Badary, Osama A

Tadros, Samer A; Attia, Yasmin M; Maurice, Nadine W; Fahim, Sally A; Abdelwahed, Fatma M; Ibrahim, Samar; Badary, Osama A.

Afiliação

Tadros SA; Department of Biochemistry, Faculty of Pharmacy, October University for Modern Sciences and Arts (MSA), 26 July Mehwar Road Intersection with Wahat Road, 6th of October City P.O. Box 12451, Egypt.
Attia YM; Pharmacology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo P.O. Box 11796, Egypt.
Maurice NW; Department of Biochemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini Street, Cairo P.O. Box 11562, Egypt.
Fahim SA; Department of Biochemistry, School of Pharmacy, Newgiza University (NGU), Newgiza, Km 22 Cairo-Alexandria Desert Road, Giza P.O. Box 12577, Egypt.
Abdelwahed FM; Medical Biochemistry and Molecular Biology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Kasr Al Eini Street, Fom El Khalig, Cairo P.O. Box 11796, Egypt.
Ibrahim S; Clinical Pharmacy Practice Department, Ahram Canadian University, 4th Industrial Zone, Banks Complex, 6th of October City P.O. Box 12451, Egypt.
Badary OA; Clinical Pharmacy Practice Department, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo P.O. Box 12508, Egypt.

Int J Mol Sci ; 23(24)2022 Dec 14.

Article em En | MEDLINE | ID: mdl-36555545

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; MicroRNAs; Ratos; Animais; Carcinoma Hepatocelular/tratamento farmacológico; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Neoplasias Hepáticas/tratamento farmacológico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Metaloproteinase 2 da Matriz/genética; Metaloproteinase 2 da Matriz/metabolismo; Metaloproteinase 9 da Matriz/genética; Metaloproteinase 9 da Matriz/metabolismo; Fator A de Crescimento do Endotélio Vascular/genética; Fator A de Crescimento do Endotélio Vascular/metabolismo; MicroRNAs/metabolismo; Regulação Neoplásica da Expressão Gênica

Palavras-chave

TIMP3; angiogenesis; diethylnitrosamine; liver cancer; miR-1-3p; thymoquinone

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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