Echinacoside exerts its protective effects in a type 2 diabetes mellitus injury model via the AKT pathway.
J Asian Nat Prod Res
; 25(9): 880-889, 2023 Sep.
Article
em En
| MEDLINE
| ID: mdl-36573490
ABSTRACT
Echinacoside (ECH) is the main compound of Cistanche deserticola, which possesses antioxidant, antitumor, antifatigue, and anti-inflammatory properties. The present study investigated the protective effects of echinacoside on type 2 diabetes mellitus (T2DM)-induced injury in T2DM injury db/db mice model and insulin-resistant LO2 cell model. The results demonstrated that ECH probably alleviated T2DM-induced injury by mediating the AKT pathway, which provided a new direction for the treatment of T2DM-induced injury.
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01-internacional
Base de dados:
MEDLINE
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article