OLMALINC/OCT4/BMP2 axis enhances osteogenic-like phenotype of renal interstitial fibroblasts to participate in Randall's plaque formation.

Zhu, Zewu; Huang, Fang; Jiang, Yingcheng; Ruan, Shuhao; Liu, Minghui; Zhang, Youjie; Li, Yongchao; Chen, Jinbo; Cui, Yu; Chen, Zhiyong; Chen, Hequn; Zeng, Feng

Zhu, Zewu; Huang, Fang; Jiang, Yingcheng; Ruan, Shuhao; Liu, Minghui; Zhang, Youjie; Li, Yongchao; Chen, Jinbo; Cui, Yu; Chen, Zhiyong; Chen, Hequn; Zeng, Feng.

Afiliação

Zhu Z; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Huang F; Department of Internal Medicine, Section Endocrinology, Yale University School of Medicine, New Haven, CT, USA.
Jiang Y; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Ruan S; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Liu M; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Zhang Y; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Li Y; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen J; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Cui Y; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen Z; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Chen H; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Zeng F; Department of Urology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.

Mol Med ; 28(1): 162, 2022 12 29.

Article em En | MEDLINE | ID: mdl-36581839

Assuntos

Proteína Morfogenética Óssea 2; Cálculos Renais; Fator 3 de Transcrição de Octâmero; RNA Longo não Codificante; Humanos; Proteína Morfogenética Óssea 2/genética; Oxalato de Cálcio/metabolismo; Fibroblastos/metabolismo; Rim/metabolismo; Cálculos Renais/metabolismo; Medula Renal/patologia; Fenótipo; RNA Longo não Codificante/genética; Fator 3 de Transcrição de Octâmero/genética

Palavras-chave

BMP2; OCT4; OLMALINC; Osteogenic-like differentiation; Randall's plaques; Renal interstitial fibroblasts

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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