A diet enriched in omega-3 PUFA and inulin prevents type 1 diabetes by restoring gut barrier integrity and immune homeostasis in NOD mice.

Lo Conte, Marta; Antonini Cencicchio, Martina; Ulaszewska, Marynka; Nobili, Angelica; Cosorich, Ilaria; Ferrarese, Roberto; Massimino, Luca; Andolfo, Annapaola; Ungaro, Federica; Mancini, Nicasio; Falcone, Marika

Lo Conte, Marta; Antonini Cencicchio, Martina; Ulaszewska, Marynka; Nobili, Angelica; Cosorich, Ilaria; Ferrarese, Roberto; Massimino, Luca; Andolfo, Annapaola; Ungaro, Federica; Mancini, Nicasio; Falcone, Marika.

Afiliação

Lo Conte M; Autoimmune Pathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Antonini Cencicchio M; Università Vita-Salute San Raffaele, Milan, Italy.
Ulaszewska M; Autoimmune Pathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Nobili A; Università Vita-Salute San Raffaele, Milan, Italy.
Cosorich I; Proteomics and Metabolomics Facility (ProMeFa), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ferrarese R; Autoimmune Pathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Massimino L; Autoimmune Pathogenesis Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Andolfo A; Laboratory of Medical Microbiology and Virology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Ungaro F; Experimental Gastroenterology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Mancini N; Proteomics and Metabolomics Facility (ProMeFa), IRCCS San Raffaele Scientific Institute, Milan, Italy.
Falcone M; Experimental Gastroenterology Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Front Immunol ; 13: 1089987, 2022.

Article em En | MEDLINE | ID: mdl-36713378

Assuntos

Diabetes Mellitus Tipo 1; Camundongos; Animais; Camundongos Endogâmicos NOD; Inulina/farmacologia; Dieta; Inflamação; Homeostase; Anti-Inflamatórios

Palavras-chave

Type 1 diabetes; anti-inflammatory diet (AID); gut barrier integrity; gut microbiota; mucus layer; regulatory T cells

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article