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Necrotizing Scleritis and Rheumatoid Arthritis: A Clinical Case Report Supported by A Brief Review with Risk of Bias Analysis.
Busnelo Moreno, Celso; Gonçalves Cruz, João Carlos; Zotarelli-Filho, Idiberto Jose; de Lima Batista Ribeiro Junior, Maurélio; Colombo Barboza, Marcello Novoa; Colombo Barboza, Guilherme Novoa; Gouvêa Barioni, Marta Fabiane.
Afiliação
  • Busnelo Moreno C; Department of Ophtalmology, Laser Vision Ophthalmological Hospital, Santos, Sao Paulo, Brazil.
  • Gonçalves Cruz JC; Department of Ophtalmology, Laser Vision Ophthalmological Hospital, Santos, Sao Paulo, Brazil.
  • Zotarelli-Filho IJ; Department of Clinical Research, Faculty of Medicine of Sao Jose do Rio Preto, FACERES, Sao Paulo, Brazil.
  • de Lima Batista Ribeiro Junior M; Department of Ophtalmology, Laser Vision Ophthalmological Hospital, Santos, Sao Paulo, Brazil.
  • Colombo Barboza MN; Department of Ophtalmology, Laser Vision Ophthalmological Hospital, Santos, Sao Paulo, Brazil.
  • Colombo Barboza GN; Department of Ophtalmology, Laser Vision Ophthalmological Hospital, Santos, Sao Paulo, Brazil.
  • Gouvêa Barioni MF; Department of Ophtalmology, Laser Vision Ophthalmological Hospital, Santos, Sao Paulo, Brazil.
Curr Rheumatol Rev ; 19(3): 367-372, 2023 Jun 05.
Article em En | MEDLINE | ID: mdl-36809968
INTRODUCTION: Necrotizing scleritis (NS) presents 30%-40% as having a systemic autoimmune condition. OBJECTIVE: To present a clinical case report and a systematic review of necrotizing scleritis with ocular manifestation as the first sign of rheumatologic disease. METHODS: The present study was elaborated according to the rules of CARE. CASE REPORT: A female patient, 63 years old, a white, administrative assistant, presented irritation, low visual acuity (LVA) in the left eye (LE), and headache. Biomicroscopy (BIO) in the right eye (RE) was normal, and the LE showed hyperemia and scleral thinning. After 1 month, the patient returns without signs of infectious diseases in the exams, and after a rheumatological evaluation with a diagnosis of rheumatoid arthritis, methotrexate and prednisone are prescribed. After 2 months, she relapsed and started treatment with anti-TNF, with remission after the 4th dose. After 1 year, she evolved with LVA in LE. RESULTS: A total of 244 articles were found, 104 articles were evaluated and 10 were included in the brief review. The symmetrical Funnel Plot does not suggest a risk of bias. CONCLUSION: Both in the present case report and the literary findings, it was evidenced that the ophthalmologic findings may precede the systemic changes of the disease for the early diagnosis of rheumatoid arthritis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies / Systematic_reviews Limite: Female / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies / Screening_studies / Systematic_reviews Limite: Female / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article