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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery.
Abdelazeem, Heba; Tu, Ly; Thuillet, Raphaël; Ottaviani, Mina; Boulfrad, Achraf; Beck, Thomas; Senbel, Amira; Mani, Salma; Castier, Yves; Guyard, Alice; Tran-Dinh, Alexy; El-Benna, Jamel; Longrois, Dan; Silverstein, Adam M; Guignabert, Christophe; Norel, Xavier.
Afiliação
  • Abdelazeem H; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria University, Egypt.
  • Tu L; INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies¼, Hôpital Marie Lannelongue, 92350, Le Plessis-Robinson, France; Université Paris-Saclay, Faculté de Médecine, 94270, Le Kremlin-Bicêtre, France.
  • Thuillet R; INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies¼, Hôpital Marie Lannelongue, 92350, Le Plessis-Robinson, France; Université Paris-Saclay, Faculté de Médecine, 94270, Le Kremlin-Bicêtre, France.
  • Ottaviani M; INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies¼, Hôpital Marie Lannelongue, 92350, Le Plessis-Robinson, France; Université Paris-Saclay, Faculté de Médecine, 94270, Le Kremlin-Bicêtre, France.
  • Boulfrad A; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France.
  • Beck T; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France.
  • Senbel A; Arab Academy for Science, Technology & Maritime Transport, College of Pharmacy, Alexandria, Egypt.
  • Mani S; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France; Université de Monastir-Tunisia, Institut Supérieur de Biotechnologie de Monastir (ISBM), Tunisia.
  • Castier Y; Hôpital Bichat-Claude Bernard, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
  • Guyard A; Hôpital Bichat-Claude Bernard, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
  • Tran-Dinh A; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France; Hôpital Bichat-Claude Bernard, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
  • El-Benna J; Université Paris Cité, INSERM-U1149, CNRS-ERL8252, Centre de Recherche sur l'Inflammation, Laboratoire d'Excellence Inflamex, Faculté de Médecine, Site Xavier Bichat, Paris, F-75018, France.
  • Longrois D; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France; Hôpital Bichat-Claude Bernard, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
  • Silverstein AM; United Therapeutics, Research Triangle Park, NC, 27709, USA.
  • Guignabert C; INSERM UMR_S 999 «Pulmonary Hypertension: Pathophysiology and Novel Therapies¼, Hôpital Marie Lannelongue, 92350, Le Plessis-Robinson, France; Université Paris-Saclay, Faculté de Médecine, 94270, Le Kremlin-Bicêtre, France.
  • Norel X; Université Paris Cité and Université Sorbonne Paris Nord, INSERM, LVTS, F-75018, Paris, France. Electronic address: xavier.norel@inserm.fr.
Eur J Pharmacol ; 946: 175579, 2023 May 05.
Article em En | MEDLINE | ID: mdl-36914083
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article