Adverse impact of a high CD4/CD8 ratio in the allograft may be overcome by methotrexate- but not mycophenolate- or post-transplant cyclophosphamide-based graft versus host disease prophylaxis.

Nikoloudis, A; Buxhofer-Ausch, V; Aichinger, C; Binder, M; Hasengruber, P; Kaynak, E; Wipplinger, D; Milanov, R; Strassl, I; Stiefel, O; Machherndl-Spandl, S; Petzer, A; Weltermann, A; Clausen, J

Nikoloudis, A; Buxhofer-Ausch, V; Aichinger, C; Binder, M; Hasengruber, P; Kaynak, E; Wipplinger, D; Milanov, R; Strassl, I; Stiefel, O; Machherndl-Spandl, S; Petzer, A; Weltermann, A; Clausen, J.

Afiliação

Nikoloudis A; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Buxhofer-Ausch V; Johannes Kepler University, Medical Faculty, Linz, Austria.
Aichinger C; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Binder M; Johannes Kepler University, Medical Faculty, Linz, Austria.
Hasengruber P; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Kaynak E; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Wipplinger D; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Milanov R; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Strassl I; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Stiefel O; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Machherndl-Spandl S; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Petzer A; Johannes Kepler University, Medical Faculty, Linz, Austria.
Weltermann A; Ordensklinikum Linz-Elisabethinen, Department of Internal Medicine I: Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Linz, Austria.
Clausen J; Johannes Kepler University, Medical Faculty, Linz, Austria.

Eur J Haematol ; 110(6): 715-724, 2023 Jun.

Article em En | MEDLINE | ID: mdl-36941654

Assuntos

Doença Enxerto-Hospedeiro; Transplante de Células-Tronco Hematopoéticas; Humanos; Aloenxertos; Linfócitos T CD8-Positivos; Ciclofosfamida/efeitos adversos; Ciclosporina/uso terapêutico; Doença Enxerto-Hospedeiro/diagnóstico; Doença Enxerto-Hospedeiro/etiologia; Doença Enxerto-Hospedeiro/prevenção & controle; Transplante de Células-Tronco Hematopoéticas/efeitos adversos; Imunossupressores/uso terapêutico; Metotrexato/uso terapêutico; Ácido Micofenólico/uso terapêutico; Estudos Retrospectivos; Linfócitos T CD4-Positivos

Palavras-chave

CD4/CD8 ratio; allograft composition; survival

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google