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Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes.
Gericke, Lukas; Mhaindarkar, Dipali; Karst, Lukas C; Jahn, Sören; Kuge, Marco; Mohr, Michael K F; Gagsteiger, Jana; Cornelissen, Nicolas V; Wen, Xiaojin; Mordhorst, Silja; Jessen, Henning J; Rentmeister, Andrea; Seebeck, Florian P; Layer, Gunhild; Loenarz, Christoph; Andexer, Jennifer N.
Afiliação
  • Gericke L; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Mhaindarkar D; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Karst LC; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Jahn S; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Kuge M; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Mohr MKF; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Gagsteiger J; Institute of Pharmaceutical Sciences, Pharmaceutical Biology, University of Freiburg, Stefan-Meier-Str. 19, 79104, Freiburg, Germany.
  • Cornelissen NV; Institute of Biochemistry, University of Münster, Corrensstr. 36, 48149, Münster, Germany.
  • Wen X; Department of Chemistry, University of Basel, Mattenstr. 22, 4058, Basel, Switzerland.
  • Mordhorst S; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
  • Jessen HJ; Present address: Pharmaceutical Institute, Pharmaceutical Biology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany.
  • Rentmeister A; Institute of Organic Chemistry, University of Freiburg, Albertstr. 21, 79104, Freiburg, Germany.
  • Seebeck FP; Institute of Biochemistry, University of Münster, Corrensstr. 36, 48149, Münster, Germany.
  • Layer G; Department of Chemistry, University of Basel, Mattenstr. 22, 4058, Basel, Switzerland.
  • Loenarz C; Institute of Pharmaceutical Sciences, Pharmaceutical Biology, University of Freiburg, Stefan-Meier-Str. 19, 79104, Freiburg, Germany.
  • Andexer JN; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
Chembiochem ; 24(9): e202300133, 2023 05 02.
Article em En | MEDLINE | ID: mdl-36942622
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article