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Proteomic data and structure analysis combined reveal interplay of structural rigidity and flexibility on selectivity of cysteine cathepsins.
Tusar, Livija; Loboda, Jure; Impens, Francis; Sosnowski, Piotr; Van Quickelberghe, Emmy; Vidmar, Robert; Demol, Hans; Sedeyn, Koen; Saelens, Xavier; Vizovisek, Matej; Mihelic, Marko; Fonovic, Marko; Horvat, Jaka; Kosec, Gregor; Turk, Boris; Gevaert, Kris; Turk, Dusan.
Afiliação
  • Tusar L; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Loboda J; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins (CIPKeBiP), Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Impens F; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Sosnowski P; The Jozef Stefan International Postgraduate School, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Van Quickelberghe E; VIB-UGent Center for Medical Biotechnology and UGent Department of Biomolecular Medicine, Technologiepark-Zwijnaarde 75, 9052, Ghent, Belgium.
  • Vidmar R; Centre of Excellence for Integrated Approaches in Chemistry and Biology of Proteins (CIPKeBiP), Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Demol H; VIB-UGent Center for Medical Biotechnology and UGent Department of Biomolecular Medicine, Technologiepark-Zwijnaarde 75, 9052, Ghent, Belgium.
  • Sedeyn K; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Saelens X; VIB-UGent Center for Medical Biotechnology and UGent Department of Biomolecular Medicine, Technologiepark-Zwijnaarde 75, 9052, Ghent, Belgium.
  • Vizovisek M; VIB-UGent Center for Medical Biotechnology and, Department for Biochemistry and Microbiology, Ghent University, 9052, Ghent, Belgium.
  • Mihelic M; VIB-UGent Center for Medical Biotechnology and, Department for Biochemistry and Microbiology, Ghent University, 9052, Ghent, Belgium.
  • Fonovic M; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Horvat J; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Kosec G; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
  • Turk B; Acies Bio d.o.o., Tehnoloski park 21, 1000, Ljubljana, Slovenia.
  • Gevaert K; Acies Bio d.o.o., Tehnoloski park 21, 1000, Ljubljana, Slovenia.
  • Turk D; Jozef Stefan Institute, Department of Biochemistry and Molecular and Structural Biology, Jamova cesta 39, 1000, Ljubljana, Slovenia.
Commun Biol ; 6(1): 450, 2023 04 24.
Article em En | MEDLINE | ID: mdl-37095140

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article