Single-cell profiling of low-stage endometrial cancers identifies low epithelial vimentin expression as a marker of recurrent disease.

Lien, Hilde E; Berg, Hege F; Halle, Mari K; Trovik, Jone; Haldorsen, Ingfrid S; Akslen, Lars A; Krakstad, Camilla

Lien, Hilde E; Berg, Hege F; Halle, Mari K; Trovik, Jone; Haldorsen, Ingfrid S; Akslen, Lars A; Krakstad, Camilla.

Afiliação

Lien HE; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Berg HF; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Halle MK; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Trovik J; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
Haldorsen IS; Mohn Medical Imaging and Visualization Centre, Department of Radiology, Haukeland University Hospital, Bergen, Norway; Section for Radiology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Akslen LA; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Pathology, Haukeland University Hospital, Bergen, Norway.
Krakstad C; Centre for Cancer Biomarkers, Department of Clinical Science, University of Bergen, Bergen, Norway; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway. Electronic address: camilla.krakstad@uib.no.

EBioMedicine ; 92: 104595, 2023 Jun.

Article em En | MEDLINE | ID: mdl-37146405

Assuntos

Neoplasias do Endométrio; Humanos; Feminino; Vimentina/genética; Vimentina/metabolismo; Neoplasias do Endométrio/diagnóstico; Neoplasias do Endométrio/genética; Neoplasias do Endométrio/metabolismo; Endométrio; Biomarcadores Tumorais/genética; Doença Crônica; Prognóstico

Palavras-chave

Endometrial cancer; FIGO I; Imaging mass cytometry; Prognosis; Recurrence; Tumor heterogeneity; Vimentin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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