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Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief.
Hegron, Alan; Peach, Chloe J; Tonello, Raquel; Seemann, Philipp; Teng, Shavonne; Latorre, Rocco; Huebner, Harald; Weikert, Dorothee; Rientjes, Jeanette; Veldhuis, Nicholas A; Poole, Daniel P; Jensen, Dane D; Thomsen, Alex R B; Schmidt, Brian L; Imlach, Wendy L; Gmeiner, Peter; Bunnett, Nigel W.
Afiliação
  • Hegron A; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
  • Peach CJ; Department of Neuroscience and Physiology, Neuroscience Institute, New York University, New York, NY 10010.
  • Tonello R; Pain Research Center, College of Dentistry, New York University, New York, NY 10010.
  • Seemann P; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
  • Teng S; Department of Neuroscience and Physiology, Neuroscience Institute, New York University, New York, NY 10010.
  • Latorre R; Pain Research Center, College of Dentistry, New York University, New York, NY 10010.
  • Huebner H; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
  • Weikert D; Department of Neuroscience and Physiology, Neuroscience Institute, New York University, New York, NY 10010.
  • Rientjes J; Pain Research Center, College of Dentistry, New York University, New York, NY 10010.
  • Veldhuis NA; Department of Chemistry and Pharmacy, Friedrich-Alexander Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
  • Poole DP; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
  • Jensen DD; Department of Neuroscience and Physiology, Neuroscience Institute, New York University, New York, NY 10010.
  • Thomsen ARB; Pain Research Center, College of Dentistry, New York University, New York, NY 10010.
  • Schmidt BL; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, NY 10010.
  • Imlach WL; Department of Neuroscience and Physiology, Neuroscience Institute, New York University, New York, NY 10010.
  • Gmeiner P; Pain Research Center, College of Dentistry, New York University, New York, NY 10010.
  • Bunnett NW; Department of Chemistry and Pharmacy, Friedrich-Alexander Universität Erlangen-Nürnberg, 91058, Erlangen, Germany.
Proc Natl Acad Sci U S A ; 120(22): e2220979120, 2023 05 30.
Article em En | MEDLINE | ID: mdl-37216510
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article