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Genetically engineering endothelial niche in human kidney organoids enables multilineage maturation, vascularization and de novo cell types.
Maggiore, Joseph C; LeGraw, Ryan; Przepiorski, Aneta; Velazquez, Jeremy; Chaney, Christopher; Streeter, Evan; Silva-Barbosa, Anne; Franks, Jonathan; Hislop, Joshua; Hill, Alex; Wu, Haojia; Pfister, Katherine; Howden, Sara E; Watkins, Simon C; Little, Melissa; Humphreys, Benjamin D; Watson, Alan; Stolz, Donna B; Kiani, Samira; Davidson, Alan J; Carroll, Thomas J; Cleaver, Ondine; Sims-Lucas, Sunder; Ebrahimkhani, Mo R; Hukriede, Neil A.
Afiliação
  • Maggiore JC; Department of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA.
  • LeGraw R; Department of Pathology, Division of Experimental Pathology, School of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA.
  • Przepiorski A; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Velazquez J; Department of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA.
  • Chaney C; Department of Pathology, Division of Experimental Pathology, School of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA.
  • Streeter E; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Silva-Barbosa A; Department of Molecular Biology and Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Franks J; Department of Internal Medicine, Division of Nephrology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  • Hislop J; Department of Developmental Biology, School of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA.
  • Hill A; Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh PA, 15213.
  • Wu H; Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Pfister K; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Howden SE; Department of Bioengineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Watkins SC; Department of Pathology, Division of Experimental Pathology, School of Medicine, University of Pittsburgh, Pittsburgh PA 15213, USA.
  • Little M; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA 15261, USA.
  • Humphreys BD; Division of Nephrology, Department of Medicine, School of Medicine, Washington University in St. Louis, St. Louis, MO 63130.
  • Watson A; Department of Pediatrics, School of Medicine, University of Pittsburgh, Pittsburgh PA, 15213.
  • Stolz DB; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
  • Kiani S; Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA 15213, USA.
  • Davidson AJ; Murdoch Children's Research Institute, Melbourne, Victoria, Australia.
  • Carroll TJ; Department of Anatomy and Neuroscience, The University of Melbourne, Melbourne, Victoria, Australia.
  • Cleaver O; Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.
  • Sims-Lucas S; Division of Nephrology, Department of Medicine, School of Medicine, Washington University in St. Louis, St. Louis, MO 63130.
  • Ebrahimkhani MR; Department of Developmental Biology, School of Medicine, Washington University in St. Louis, St. Louis, MO 63130.
  • Hukriede NA; Center for Biologic Imaging, University of Pittsburgh, Pittsburgh, PA 15213, USA.
bioRxiv ; 2023 May 30.
Article em En | MEDLINE | ID: mdl-37333155
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Ano de publicação: 2023 Tipo de documento: Article