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Ketolysis drives CD8+ T cell effector function through effects on histone acetylation.
Luda, Katarzyna M; Longo, Joseph; Kitchen-Goosen, Susan M; Duimstra, Lauren R; Ma, Eric H; Watson, McLane J; Oswald, Brandon M; Fu, Zhen; Madaj, Zachary; Kupai, Ariana; Dickson, Bradley M; DeCamp, Lisa M; Dahabieh, Michael S; Compton, Shelby E; Teis, Robert; Kaymak, Irem; Lau, Kin H; Kelly, Daniel P; Puchalska, Patrycja; Williams, Kelsey S; Krawczyk, Connie M; Lévesque, Dominique; Boisvert, François-Michel; Sheldon, Ryan D; Rothbart, Scott B; Crawford, Peter A; Jones, Russell G.
Afiliação
  • Luda KM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA; University of Copenhagen, Novo Nordisk Foundation Center for Basic Metabolic Research, Blegdamsvej 3B, 2200 København, Denmark.
  • Longo J; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Kitchen-Goosen SM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Duimstra LR; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Ma EH; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Watson MJ; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Oswald BM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Fu Z; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Madaj Z; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Kupai A; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Dickson BM; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • DeCamp LM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Dahabieh MS; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Compton SE; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Teis R; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Kaymak I; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Lau KH; Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Kelly DP; Cardiovascular Institute and Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Puchalska P; Department of Medicine, Division of Molecular Medicine, University of Minnesota, Minneapolis, MN 55455, USA.
  • Williams KS; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Krawczyk CM; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Lévesque D; Department of Anatomy and Cell Biology, Université de Sherbrooke, Sherbrooke, QC J1E 4K8, Canada.
  • Boisvert FM; Department of Anatomy and Cell Biology, Université de Sherbrooke, Sherbrooke, QC J1E 4K8, Canada.
  • Sheldon RD; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Rothbart SB; Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.
  • Crawford PA; Department of Medicine, Division of Molecular Medicine, University of Minnesota, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.
  • Jones RG; Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI 49503, USA. Electronic address: russell.jones@vai.org.
Immunity ; 56(9): 2021-2035.e8, 2023 09 12.
Article em En | MEDLINE | ID: mdl-37516105
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article