Core Fucosylation Mediated by the FucT-8 Enzyme Affects TRAIL-Induced Apoptosis and Sensitivity to Chemotherapy in Human SW480 and SW620 Colorectal Cancer Cells.

López-Cortés, Rubén; Correa Pardo, Isabel; Muinelo-Romay, Laura; Fernández-Briera, Almudena; Gil-Martín, Emilio

López-Cortés, Rubén; Correa Pardo, Isabel; Muinelo-Romay, Laura; Fernández-Briera, Almudena; Gil-Martín, Emilio.

Afiliação

López-Cortés R; Doctoral Program in Methods and Applications in Life Sciences, Faculty of Biology, Universidade de Vigo, Campus Lagoas-Marcosende, ES36310 Vigo, Spain.
Correa Pardo I; Master Program in Advanced Biotechnology, Faculty of Biology, Universidade de Vigo, Campus Lagoas-Marcosende, ES36310 Vigo, Spain.
Muinelo-Romay L; Liquid Biopsy Analysis Unit, Translational Medical Oncology (Oncomet), Health Research Institute of Santiago de Compostela (IDIS), CIBERONC, Travesía da Choupana, ES15706 Santiago de Compostela, Spain.
Fernández-Briera A; Department of Biochemistry, Genetics and Immunology, Faculty of Biology, Universidade de Vigo, Campus Lagoas-Marcosende, ES36310 Vigo, Spain.
Gil-Martín E; Department of Biochemistry, Genetics and Immunology, Faculty of Biology, Universidade de Vigo, Campus Lagoas-Marcosende, ES36310 Vigo, Spain.

Int J Mol Sci ; 24(15)2023 Jul 25.

Article em En | MEDLINE | ID: mdl-37569254

Assuntos

Neoplasias Colorretais; Fucosiltransferases; Animais; Humanos; Fucosiltransferases/genética; Fucosiltransferases/metabolismo; Irinotecano; Oxaliplatina; Apoptose/genética; Linhagem Celular Tumoral; Neoplasias Colorretais/tratamento farmacológico; Mamíferos/metabolismo

Palavras-chave

DR4; FUT8 knockdown; TRAIL-induced apoptosis; colorectal cancer; core fucosylation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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