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A machine learning strategy for the identification of key in silico descriptors and prediction models for IgG monoclonal antibody developability properties.
Waight, Andrew B; Prihoda, David; Shrestha, Rojan; Metcalf, Kevin; Bailly, Marc; Ancona, Marco; Widatalla, Talal; Rollins, Zachary; Cheng, Alan C; Bitton, Danny A; Fayadat-Dilman, Laurence.
Afiliação
  • Waight AB; Discovery Biologics, Protein Sciences, Merck & Co., Inc, South San Francisco, CA, USA.
  • Prihoda D; Discovery Informatics, MSD Czech Republic s.r.o, Prague, Czech Republic.
  • Shrestha R; Discovery Biologics, Protein Sciences, Merck & Co., Inc, South San Francisco, CA, USA.
  • Metcalf K; Discovery Biologics, Protein Sciences, Merck & Co., Inc, South San Francisco, CA, USA.
  • Bailly M; Discovery Biologics, Protein Sciences, Merck & Co., Inc, South San Francisco, CA, USA.
  • Ancona M; Discovery Informatics, MSD Czech Republic s.r.o, Prague, Czech Republic.
  • Widatalla T; Computational and Structural Chemistry, Merck & Co., Inc, South San Francisco, CA, USA.
  • Rollins Z; Computational and Structural Chemistry, Merck & Co., Inc, South San Francisco, CA, USA.
  • Cheng AC; Computational and Structural Chemistry, Merck & Co., Inc, South San Francisco, CA, USA.
  • Bitton DA; Discovery Informatics, MSD Czech Republic s.r.o, Prague, Czech Republic.
  • Fayadat-Dilman L; Discovery Biologics, Protein Sciences, Merck & Co., Inc, South San Francisco, CA, USA.
MAbs ; 15(1): 2248671, 2023.
Article em En | MEDLINE | ID: mdl-37610144
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article