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Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity.
Syed, Aleem; Filandr, Frantisek; Patterson-Fortin, Jeffrey; Bacolla, Albino; Ravindranathan, Ramya; Zhou, Jia; McDonald, Drew T; Albuhluli, Mohammed E; Verway-Cohen, Amy; Newman, Joseph A; Tsai, Miaw-Sheue; Jones, Darin E; Schriemer, David C; D'Andrea, Alan D; Tainer, John A.
Afiliação
  • Syed A; Division of Radiation and Genome Instability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Filandr F; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB T2N 4N1, Canada.
  • Patterson-Fortin J; Division of Radiation and Genome Instability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Bacolla A; Department of Molecular and Cellular Oncology, Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
  • Ravindranathan R; Division of Radiation and Genome Instability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Zhou J; Division of Radiation and Genome Instability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • McDonald DT; Biological and System Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Albuhluli ME; Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Verway-Cohen A; Biological and System Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Newman JA; Center for Medicines Discovery, University of Oxford, OX1 3QU, UK.
  • Tsai MS; Biological and System Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
  • Jones DE; Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
  • Schriemer DC; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB T2N 4N1, Canada.
  • D'Andrea AD; Division of Radiation and Genome Instability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
  • Tainer JA; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Nucleic Acids Res ; 51(18): 9920-9937, 2023 Oct 13.
Article em En | MEDLINE | ID: mdl-37665033
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article