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Evaluation of the effects of exogenous cortisol manipulation and the glucocorticoid antagonist, RU486, on the exploratory tendency of bluegill sunfish (Lepomis macrochirus).
Carbajal, Annaïs; Lawrence, Michael J; Gilmour, Kathleen M; Lopez-Bejar, Manel; Cooke, Steven J.
Afiliação
  • Carbajal A; Department of Animal Health and Anatomy, Veterinary Faculty, UniversitatAutònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain. anais.carbajal@uab.cat.
  • Lawrence MJ; Fish Ecology and Conservation Physiology Laboratory, Department of Biology, Carleton University, Ottawa, ON, Canada.
  • Gilmour KM; Department of Biological Sciences, University of Manitoba, Winnipeg, MB, Canada.
  • Lopez-Bejar M; Department of Biology, University of Ottawa, Ottawa, ON, Canada.
  • Cooke SJ; Department of Animal Health and Anatomy, Veterinary Faculty, UniversitatAutònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain.
Fish Physiol Biochem ; 49(6): 1187-1198, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37819483
In teleost fishes, activation of the hypothalamic-pituitary-interrenal axis leads to an elevation of circulating cortisol levels as a primary stress response. While acute elevation of cortisol is generally beneficial, long-term elevation, a common characteristic of chronic stress, may lead to detrimental effects on health and physiological performance in fishes. Some stress-mediated behavioural shifts, such as variation along the shy-boldness axis in fish, may influence individual fitness. The present study evaluated the role of cortisol and its mechanisms of action in the exploratory behaviour of the bluegill sunfish (Lepomis macrochirus). Fish were implanted with cocoa butter alone (sham treatment), or cocoa butter containing cortisol, or cortisol and the glucocorticoid receptor antagonist, RU486. A control (untreated) group was also used. Animals were held for 48 h following treatment and then were subjected to a Z-maze trial to characterize the exploratory behaviour. Cortisol treatment had no measurable effect on the exploratory behaviour of bluegill sunfish. Despite presenting a higher probability of refuge emergence, fish treated with cortisol combined with RU486 behaved similarly to cortisol-treated and control groups. While these results suggest that cortisol may not be involved in the mechanisms controlling boldness, the influence of cortisol elevation across longer time periods plus validation in different contexts will be necessary to confirm this conclusion.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article