Mdivi1 ameliorates mitochondrial dysfunction in non-alcoholic steatohepatitis by inhibiting JNK/MFF signaling.

Quan, Ying; Shou, Diwen; Yang, Siqi; Cheng, Jiemin; Li, Yongqiang; Huang, Chen; Chen, Huiting; Zhou, Yongjian

Quan, Ying; Shou, Diwen; Yang, Siqi; Cheng, Jiemin; Li, Yongqiang; Huang, Chen; Chen, Huiting; Zhou, Yongjian.

Afiliação

Quan Y; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou, China.
Shou D; Department of Gastroenterology and Hepatology, Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Yang S; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou, China.
Cheng J; Department of Gastroenterology and Hepatology, Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Li Y; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou, China.
Huang C; Department of Gastroenterology and Hepatology, Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Chen H; Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, Guangzhou, China.
Zhou Y; Department of Gastroenterology and Hepatology, Second Affiliated Hospital, School of Medicine, South China University of Technology, Guangzhou, China.

J Gastroenterol Hepatol ; 38(12): 2215-2227, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37839851

Assuntos

Doenças Mitocondriais; Hepatopatia Gordurosa não Alcoólica; Camundongos; Animais; Hepatopatia Gordurosa não Alcoólica/tratamento farmacológico; Hepatopatia Gordurosa não Alcoólica/etiologia; Hepatopatia Gordurosa não Alcoólica/metabolismo; Fígado/metabolismo; Citocinas/metabolismo; Mitocôndrias/metabolismo; Fatores de Transcrição/metabolismo; Colina/metabolismo; Dinaminas; Doenças Mitocondriais/metabolismo; Camundongos Endogâmicos C57BL; Metionina; Modelos Animais de Doenças

Palavras-chave

JNK/MFF signaling; Mdivi1; Mitochondrial dysfunction; Non-alcoholic steatohepatitis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article