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Design and structural validation of peptide-drug conjugate ligands of the kappa-opioid receptor.
Muratspahic, Edin; Deibler, Kristine; Han, Jianming; Tomasevic, Natasa; Jadhav, Kirtikumar B; Olivé-Marti, Aina-Leonor; Hochrainer, Nadine; Hellinger, Roland; Koehbach, Johannes; Fay, Jonathan F; Rahman, Mohammad Homaidur; Hegazy, Lamees; Craven, Timothy W; Varga, Balazs R; Bhardwaj, Gaurav; Appourchaux, Kevin; Majumdar, Susruta; Muttenthaler, Markus; Hosseinzadeh, Parisa; Craik, David J; Spetea, Mariana; Che, Tao; Baker, David; Gruber, Christian W.
Afiliação
  • Muratspahic E; Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, 1090, Vienna, Austria.
  • Deibler K; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
  • Han J; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
  • Tomasevic N; Novo Nordisk Research Center Seattle, Novo Nordisk A/S, 530 Fairview Ave N #5000, Seattle, WA, 97403, USA.
  • Jadhav KB; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Olivé-Marti AL; Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, 1090, Vienna, Austria.
  • Hochrainer N; Institute of Biological Chemistry, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria.
  • Hellinger R; Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
  • Koehbach J; Department of Pharmaceutical Chemistry, Institute of Pharmacy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
  • Fay JF; Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, 1090, Vienna, Austria.
  • Rahman MH; Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Hegazy L; School of Biomedical Sciences, Faculty for Medicine, The University of Queensland, Brisbane, QLD, 4072, Australia.
  • Craven TW; Department of Biochemistry and Molecular Biology, University of Maryland Baltimore, Baltimore, MD, 21201, USA.
  • Varga BR; Department of Pharmaceutical and Administrative Sciences, Saint Louis College of Pharmacy, University of Health Sciences & Pharmacy in St. Louis, St. Louis, MO, 63110, USA.
  • Bhardwaj G; Department of Pharmaceutical and Administrative Sciences, Saint Louis College of Pharmacy, University of Health Sciences & Pharmacy in St. Louis, St. Louis, MO, 63110, USA.
  • Appourchaux K; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
  • Majumdar S; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Muttenthaler M; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Hosseinzadeh P; Institute for Protein Design, University of Washington, Seattle, WA, 98195, USA.
  • Craik DJ; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Spetea M; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Che T; Center for Clinical Pharmacology, University of Health Sciences & Pharmacy at St. Louis and Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Baker D; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, 63110, USA.
  • Gruber CW; Institute of Biological Chemistry, Faculty of Chemistry, University of Vienna, 1090, Vienna, Austria.
Nat Commun ; 14(1): 8064, 2023 Dec 06.
Article em En | MEDLINE | ID: mdl-38052802
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article