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Molecular hybrids of substituted phenylcarbamoylpiperidine and 1,2,4-triazole methylacetamide as potent 15-LOX inhibitors: Design, synthesis, DFT calculations and molecular docking studies.
Nawaz, Zahid; Riaz, Naheed; Saleem, Muhammad; Iqbal, Ambar; Abida Ejaz, Syeda; Bashir, Bushra; Muzaffar, Saima; Ashraf, Muhammad; Sajjad Bilal, Muhammad; Krishna Prabhala, Bala; Sajid, Salvia.
Afiliação
  • Nawaz Z; Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
  • Riaz N; Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. Electronic address: nrch322@yahoo.com.
  • Saleem M; Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
  • Iqbal A; Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan; Department of Biochemistry, Institute of Biochemistry, Biotechnology and Bioinformatics (IBBB), Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakist
  • Abida Ejaz S; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Khawaja Fareed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
  • Bashir B; Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
  • Muzaffar S; Department of Chemistry, Division of Sceience and Technology, University of Education, 54770 Lahore, Vehari Campus, Pakistan.
  • Ashraf M; Institute of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan. Electronic address: dr.m.ashraf@gmail.com.
  • Aziz-Ur-Rehman; Department of Chemistry, Government College University Lahore, Lahore 54000, Pakistan.
  • Sajjad Bilal M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Khawaja Fareed Campus, The Islamia University of Bahawalpur, Bahawalpur 63100, Pakistan.
  • Krishna Prabhala B; Institute of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230M, Denmark.
  • Sajid S; Department of Drug Design and Pharmacology, University of Copenhagen 2, DK-2100 Kobenhavn O, Denmark.
Bioorg Chem ; 143: 106984, 2024 Feb.
Article em En | MEDLINE | ID: mdl-38056389
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article