NRBC concentrations over time in neonates with moderate to severe neonatal encephalopathy with and without sentinel events.
J Perinatol
; 44(8): 1157-1162, 2024 Aug.
Article
em En
| MEDLINE
| ID: mdl-38287136
ABSTRACT
OBJECTIVE:
To study the serum concentrations of nucleated red blood cells (NRBC) over time in neonates with moderate to severe neonatal encephalopathy (NE). STUDYDESIGN:
A retrospective cohort study with subjects subdivided into three groups definite sentinel events (n = 52), probable sentinel events (n = 20) and no history of sentinel events (n = 63). Peak absolute NRBC and NRBC/100 WBC were compared between groups and with MRI Injury score, cord and admission pH/base deficit.RESULTS:
Absolute NRBC peaked at 24.05 h after birth (CI 15.30-32.79), 17.56 h after birth (CI 7.35-27.77), and 39.81 h after birth (CI 28.73-50.89) in each respective group. The peak in absolute NRBC correlated with the severity of injury in the grey matter in group 2 and white matter in groups 1 and 2. Higher peak absolute NRBC value correlated to a lower admission ABG pH.CONCLUSION:
NRBC peak at 24 h after birth in neonates with sentinel events.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Observational_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article