New approaches for challenging therapeutic targets.
Drug Discov Today
; 29(4): 103942, 2024 Apr.
Article
em En
| MEDLINE
| ID: mdl-38447929
ABSTRACT
Despite successes with new drug approvals over the past two decades through conventional drug development approaches, many human diseases remain intractable to current therapeutic interventions. Possible barriers may be that the complexity of the target, and disease biology, are impervious to such conventional drug development approaches. The US National Institutes of Health hosted a workshop with the goal of identifying challenges and opportunities with alternative modalities for developing treatments across diseases associated with historically undruggable targets. This report highlights key issues discussed during the workshop that, if addressed, could expand the pool of therapeutic approaches for treating various diseases.
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Coleções:
01-internacional
Base de dados:
MEDLINE
País/Região como assunto:
America do norte
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article