[Drug research and development and unmet needs for advanced-stage hepatocellular carcinoma].
Zhonghua Gan Zang Bing Za Zhi
; 32(4): 306-311, 2024 Apr 20.
Article
em Zh
| MEDLINE
| ID: mdl-38733184
ABSTRACT
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide and is a global health challenge. Radical surgical resection is the most effective method to achieve long-term survival for HCC. Regrettably, the vast majority of HCC patients lose the opportunity for radical resection at the time of diagnosis due to advanced tumors or poor liver reserve capacity. HCC is resistant to conventional chemotherapy, and in the past, there have been no definite and effective systemic therapeutic drugs. Fortunately, over the last decade, the research and development of molecular targeted therapy and immunotherapy drugs for HCC have made rapid progress, and a variety of drugs and combination therapy regimens have been successively approved for clinical use. However, the overall therapeutic effect is still not ideal and needs further improvement.
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01-internacional
Base de dados:
MEDLINE
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2024
Tipo de documento:
Article