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Comprehensive Collection of Whole-Slide Images and Genomic Profiles for Patients with Bladder Cancer.
Xu, Pei-Hang; Li, Tianqi; Qu, Fengmei; Tian, Mingkang; Wang, Jun; Gan, Hualei; Ye, Dingwei; Ren, Fei; Shen, Yijun.
Afiliação
  • Xu PH; Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Li T; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
  • Qu F; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
  • Tian M; Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.
  • Wang J; Institute of Pathology, Fudan University, Shanghai, 200032, China.
  • Gan H; Jinfeng Laboratory, Chongqing, 401329, P.R. China.
  • Ye D; Jinfeng Laboratory, Chongqing, 401329, P.R. China.
  • Ren F; Department of Urology, Sun Yat-sen University Cancer Center, Guangzhou, China.
  • Shen Y; State Key Laboratory of Oncology in Southern China, Guangzhou, China.
Sci Data ; 11(1): 699, 2024 Jun 27.
Article em En | MEDLINE | ID: mdl-38937479
ABSTRACT
Bladder cancer is one of the leading causes of cancer-related mortality in the urinary system. Understanding genomic information is important in the treatment and prognosis of bladder cancer, but the current method used to identify mutations is time-consuming and labor-intensive. There are now many novel and convenient ways to predict cancerous genomics from pathological slides. However, the publicly available datasets are limited, especially for Asian populations. In this study, we developed a dataset consisting of 75 Asian cases of bladder cancers and 112 Whole-Slide Images with one to two images obtained for each patient. This dataset provides information on the most frequently and clinically significant mutated genes derived by whole-exome sequencing in these patients. This dataset will facilitate exploration and development of novel diagnostic and therapeutic technologies for bladder cancer.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article