"Forcing" new interpretations of molecular tension sensor studies.

Pawlak, Matthew R; Smiley, Adam T; Gordon, Wendy R

Pawlak, Matthew R; Smiley, Adam T; Gordon, Wendy R.

Afiliação

Pawlak MR; University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, MN, USA.
Smiley AT; University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, MN, USA.
Gordon WR; University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics, Minneapolis, MN, USA. Electronic address: wrgordon@umn.edu.

Cell Rep Methods ; 4(7): 100821, 2024 Jul 15.

Article em En | MEDLINE | ID: mdl-39013362

ABSTRACT

ABSTRACT

Molecular tension sensors are central tools for mechanobiology studies but have limitations in interpretation. Reporting in Cell Reports Methods, Shoyer et al. discover that fluorescent protein photoswitching in concert with sensor extension may expand the use and interpretation of common force-sensing tools.

Assuntos

Técnicas Biossensoriais; Técnicas Biossensoriais/métodos; Técnicas Biossensoriais/instrumentação

Palavras-chave

CP: cell biology; CP: imaging

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article