Paternity in men with stage I testis tumors on surveillance.
J Clin Oncol
; 16(2): 733-4, 1998 Feb.
Article
em En
| MEDLINE
| ID: mdl-9469364
ABSTRACT
PURPOSE:
We report long-term paternity in men with stage I testis tumors who were managed initially by surveillance. PATIENTS ANDMETHODS:
One hundred five patients with clinical stage I nonseminomatous germ cell tumors of the testis were entered on a surveillance protocol and followed up for more than 10 years. Actual fertility potential was assessed by pregnancy.RESULTS:
Of the 105 patients, 41 (39%) have fathered children, which includes 36 of 78 (46%) patients while on active surveillance and five of 27 (19%) patients after treatment for relapse. Of 63 couples who attempted a pregnancy on surveillance or were presumed capable of impregnation (whether they tried or not), 41 (65%) were successful.CONCLUSION:
These results show that the majority of men with stage I testis tumor who are on surveillance after orchiectomy, have a suitable partner, and attempt impregnation achieve a successful pregnancy. Pregnancy rates appear to be less than reported in men who have a nerve-sparing retroperitoneal lymph node dissection (RPLND) because more patients on surveillance require treatment for relapse, which reduces their chances for pregnancy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
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Guideline
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Observational_studies
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Prognostic_studies
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Screening_studies
Limite:
Adolescent
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Adult
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Female
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Humans
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Male
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Middle aged
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Pregnancy
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article