Cognitive Function and P300 Potentials in First-Episode Schizophrenia Treated with Quetiapine and Risperidone / 中国心理卫生杂志
Chinese Mental Health Journal
; (12)1991.
Article
em Zh
| WPRIM
| ID: wpr-684708
Biblioteca responsável:
WPRO
ABSTRACT
Objective:To compare the effects of quetiapine and risperidone on cognitive function of first-episode schizophrenic patients.Methods:A randomized comparative clinical design was applied to compare the cognitive function of 67 patients with first-episode schizophrenia treated with quetiapine(n=35,25-750mg/d)and risperidone(n=32,1-7rag/d)before and after 12-week treatment.PANSS,WMS and P300 were used to evaluate adverse effects of drags and cognitive function.Results:The Long-term memory,Short-term memory,Immediate memory,Memory Quotient of first-episode schizophrenia were damaged obviously.Latency periods of P_2、N_2 and P_3 of P_(300) potentials with first-episode schizophrenia group were longer than the control group,The amplitudes of P_2 and P_3 of P_(300) potentials with first-episode schizophrenia group were lower than the control group(P
Texto completo:
1
Base de dados:
WPRIM
Tipo de estudo:
Clinical_trials
/
Prognostic_studies
Idioma:
Zh
Ano de publicação:
1991
Tipo de documento:
Article