Objective@#To explore the relationship between dietary patterns and
central precocious puberty in
children, and to provide a scientific basis for dietary prevention of
precocious puberty.@*
Methods@#A
case-control study was conducted, among 35 newly diagnosed
central precocious puberty girls from May to December 2019 as the case group, and 70 healthy
girls with normal development as the
control group. Physical development examination,
parent questionnaire survey and
child interview were carried out. Dietary information was assessed using a simplified
food frequency
questionnaire(FFQ).
Principal component analysis was used to identify
children s dietary patterns, and multiple
Logistic regression was used to assess the
association between dietary patterns and
precocious puberty.@*Results@#Three different dietary patterns have been established, namely "
snack and processed
food type", "
animal protein type" and "nutritional tonic type" dietary patterns, respectively. After adjusting for covariates such as age and BMI,
Logistic regression analysis showed that the "
snack and processed
food type" dietary pattern was positively correlated with
precocious puberty(OR=10.81, 95%CI=2.59-45.15, P<0.01). There was a negative correlation between "
animal protein type" and
precocious puberty(OR=0.24, 95%CI=0.06-0.91, P=0.04), while the
association between "nutritive tonic" and
precocious puberty was not statistically significant(OR=0.28, 95%CI=0.07-1.05, P=0.06).@*Conclusion@#
Children s dietary patterns were related to
precocious puberty."
Snack and processed
food "dietary pattern with a high intake of fried
foods, puffed
foods,
foods containing preservatives or pigments, western
fast foods,
chocolate and products, was closely related to
central precocious puberty.