RESUMEN
BACKGROUND: local estrogen treatments have been used for vaginal dryness management. The objective was to determine the maturation index (MI) and vaginal dryness after the treatment with topic conjugated estrogens (TCE) in low and conventional doses in Mexican women. METHODS: postmenopausal women that received vaginal TCE cream. Group I Low-dose which received 0.5 g of TCE twice a week and Group II Conventional-dose with one g of TCE twice a week. The MI was determined and estrogenic value (EV) was calculated. Vaginal dryness was evaluated with an analog visual scale, and vaginal humidity by the moistening of a pH test strip measured in millimeters. Statistical analysis with Student's t test for independent and paired samples was done. RESULTS: 27 women were studied, group I (n = 13), group II (n = 14). There weren't any differences in the analyzed parameters. Both treatments increased the MI and decreased the vaginal dryness. CONCLUSIONS: low and conventional dose of TCE had similar effect in vaginal scope in Mexican women.
Asunto(s)
Estrógenos Conjugados (USP)/administración & dosificación , Posmenopausia/efectos de los fármacos , Vagina/efectos de los fármacos , Vagina/fisiopatología , Femenino , Humanos , Persona de Mediana EdadRESUMEN
Cervical cancer remains a serious public health problem in the world; that is why the Mexican Federation of Schools of Obstetrics and Gynecology convened the elaboration of a consensus that is devoted this number of Ginecologia y Obstetricia de Mexico. In recent years has strengthened perceptions (public and private) in the need for preventive strategies in the medium and long terms. The development of effective vaccines against the human papilloma virus and the application of new methods of detection from viral DNA (completely automated for personal application) allow some degree of optimism. It is proposed a consensus with general recommendations in two consecutive stages: (a) primary prevention consisting of education for the prevention of cervical cancer and universal immunization and (b) secondary prevention by early detection of infections or injuries that could favor carcinogenesis. The consensus reviewed characteristics of available vaccines in detail and proposes strategies for implementation in Mexican population. Also, check out main methods of early detection of infection (or predisposing lesions) and suggests public and private strategies for implementation. Consensus places particular emphasis on early immunization for female population and correct use of methods for detection of infections or injuries that might cause cervical cancer.