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J Neurooncol ; 73(1): 89-90, 2005 May.
Artículo en Inglés | MEDLINE | ID: mdl-15933823

RESUMEN

A 24-year old primaparous female at 20 weeks gestation presented acutely with cerebellar symptoms. Magnetic resonance imaging brain showed evidence of a cerebellar vermis lesion. This was diagnosed as medulloblastoma on histopathological analysis. She underwent surgical debulking and radiotherapy. Interestingly, the lesion recurred 4 years later on her second pregnancy. She underwent further surgical debulking and adjuvant chemotherapy. We believe this is the first reported description of recurrent medulloblastoma in successive pregnancies. A brief discussion on this disease and its management in pregnancy setting is also presented.


Asunto(s)
Neoplasias Cerebelosas/diagnóstico , Meduloblastoma/diagnóstico , Recurrencia Local de Neoplasia/diagnóstico , Complicaciones Neoplásicas del Embarazo/diagnóstico , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Neoplasias Cerebelosas/tratamiento farmacológico , Neoplasias Cerebelosas/cirugía , Quimioterapia Adyuvante , Ciclofosfamida/uso terapéutico , Doxorrubicina/uso terapéutico , Etopósido/uso terapéutico , Femenino , Humanos , Ifosfamida/uso terapéutico , Meduloblastoma/tratamiento farmacológico , Meduloblastoma/cirugía , Recurrencia Local de Neoplasia/tratamiento farmacológico , Recurrencia Local de Neoplasia/cirugía , Embarazo , Complicaciones Neoplásicas del Embarazo/terapia , Resultado del Tratamiento , Vincristina/uso terapéutico
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