[The mapping of the hemagglutinin sites of the influenza viruses H3N2 isolated in 1990-1993]. / Kartirovanie saitov gemaggliutinina virusov grippa H3N2 1990--1993 gg. vydeleniia.

The antigenic structure of hemagglutinin (HA) of influenza A (H3N2) viruses was found to have undergone significant changes which markedly distinguished the new isolates of previously occurring strains. Investigations of the epidemic variants using monospecific and monoclonal antibodies revealed strains with original HA sites previously unfound in H3N2 viruses. The emergence of the sites with the new properties determined the epidemic activity of the viruses isolated in this period.

[The antigenic structure of influenza B viruses isolated in 1991]. / Antigennaia struktura virusov grippa B, vydelennykh v 1991 g.

A comparative immunological analysis of the antigenic structure of reference influenza B viruses of 1940-1984 and isolates of 1986-1991 using monospecific antibodies to individual antigenic determinants and monoclonal antibodies to hemagglutinin of B/Oregon/5/80 virus demonstrated a further antigenic drift of influenza B viruses from the reference variants B/Victoria/2/87 and B/Yamagata/16/88. Alongside with circulation of viruses with new antigenic properties, variants were found in the epidemic outbreak of 1991 whose hemagglutinin had common antigenic markers with those of variants of the previous years.