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1.
Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal.
Chem Res Toxicol
; 28(4): 817-27, 2015 Apr 20.
Artículo
Inglés
| MEDLINE | ID: mdl-25739016
2.
Peptidyl-prolyl cis/trans-isomerase A1 (Pin1) is a target for modification by lipid electrophiles.
Chem Res Toxicol
; 26(2): 270-9, 2013 Feb 18.
Artículo
Inglés
| MEDLINE | ID: mdl-23231502
3.
Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species.
J Alzheimers Dis Rep
; 6(1): 1-15, 2022.
Artículo
Inglés
| MEDLINE | ID: mdl-35243208
4.
Discovery and Early Clinical Development of LY3202626, a Low-Dose, CNS-Penetrant BACE Inhibitor.
J Med Chem
; 64(12): 8076-8100, 2021 06 24.
Artículo
Inglés
| MEDLINE | ID: mdl-34081466
5.
Preclinical Alzheimer disease: brain oxidative stress, Abeta peptide and proteomics.
Neurobiol Dis
; 39(2): 221-8, 2010 Aug.
Artículo
Inglés
| MEDLINE | ID: mdl-20399861
6.
Potential in vivo amelioration by N-acetyl-L-cysteine of oxidative stress in brain in human double mutant APP/PS-1 knock-in mice: toward therapeutic modulation of mild cognitive impairment.
J Neurosci Res
; 88(12): 2618-29, 2010 Sep.
Artículo
Inglés
| MEDLINE | ID: mdl-20648652
7.
Chemo brain (chemo fog) as a potential side effect of doxorubicin administration: role of cytokine-induced, oxidative/nitrosative stress in cognitive dysfunction.
Adv Exp Med Biol
; 678: 147-56, 2010.
Artículo
Inglés
| MEDLINE | ID: mdl-20738017
8.
Peptides and proteins in plasma and cerebrospinal fluid as biomarkers for the prediction, diagnosis, and monitoring of therapeutic efficacy of Alzheimer's disease.
Biochim Biophys Acta
; 1782(10): 549-58, 2008 Oct.
Artículo
Inglés
| MEDLINE | ID: mdl-18760351
9.
Redox proteomics analysis of brains from subjects with amnestic mild cognitive impairment compared to brains from subjects with preclinical Alzheimer's disease: insights into memory loss in MCI.
J Alzheimers Dis
; 23(2): 257-69, 2011.
Artículo
Inglés
| MEDLINE | ID: mdl-20930294
10.
2-Mercaptoethane sulfonate prevents doxorubicin-induced plasma protein oxidation and TNF-α release: implications for the reactive oxygen species-mediated mechanisms of chemobrain.
Free Radic Biol Med
; 50(11): 1630-8, 2011 Jun 01.
Artículo
Inglés
| MEDLINE | ID: mdl-21421044
11.
Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: implications for Aß accumulation in AD brain.
Free Radic Biol Med
; 49(11): 1798-803, 2010 Dec 01.
Artículo
Inglés
| MEDLINE | ID: mdl-20869432
12.
In vivo amelioration of adriamycin induced oxidative stress in plasma by gamma-glutamylcysteine ethyl ester (GCEE).
Cancer Lett
; 282(1): 25-9, 2009 Sep 08.
Artículo
Inglés
| MEDLINE | ID: mdl-19342159
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