RESUMEN
Marfan's syndrome is an inherited disorder of the connective tissue. Cardiologic manifestations, especially aortic dilation, are important causes of morbidity and mortality in the clinical course of the disease in adults and teenagers. In children, the presence of aortic aneurysm and its dissection or rupture is rare, occurring in patients with genetic mutation of the fibrillin gene but not in those who have the familial form of the disease. We describe here 2 patients, from the same family (siblings), diagnosed with gigantic aortic aneurysm early in infancy, one of them successfully undergoing surgery.
Asunto(s)
Aneurisma de la Aorta/diagnóstico , Síndrome de Marfan/diagnóstico , Hermanos , Aneurisma de la Aorta/tratamiento farmacológico , Aneurisma de la Aorta/cirugía , Niño , Resultado Fatal , Femenino , Humanos , Masculino , Síndrome de Marfan/tratamiento farmacológico , Síndrome de Marfan/cirugíaRESUMEN
OBJECTIVE: Noninvasive cardiac assessment of newborns and infants of women with systemic lupus erythematosus. The children had no congenital total atrioventricular block and were compared with the children of healthy women. METHODS: We prospectively assessed 13 newborns and infants aged 1 to 60 days, children of women with systemic lupus erythematosus and without congenital total atrioventricular block. These children were compared with 30 children of women who had no lupus or anti-Ro/SSA antibodies, and no risk factors for congenital heart disease either. Their age groups matched. The following examinations were performed: cardiological physical examination, electrocardiography, echocardiography, and signal-averaged electrocardiography. RESULTS: The statistical analysis showed no significant difference in ventricular function or in the cardiac conduction system between the groups. CONCLUSION: In regard to the conduction system and ventricular function in the absence of total atrioventricular block, no statistically significant difference was observed between the children of women with systemic lupus erythematosus and children of healthy women.
Asunto(s)
Hijo de Padres Discapacitados , Bloqueo Cardíaco/diagnóstico , Lupus Eritematoso Sistémico , Anticuerpos Antinucleares/sangre , Ecocardiografía Doppler en Color , Electrocardiografía , Femenino , Bloqueo Cardíaco/diagnóstico por imagen , Bloqueo Cardíaco/inmunología , Frecuencia Cardíaca , Humanos , Lactante , Recién Nacido , Masculino , Estudios Prospectivos , Estadísticas no ParamétricasAsunto(s)
Endocarditis Bacteriana/microbiología , Staphylococcus aureus Resistente a Meticilina , Infecciones Estafilocócicas/microbiología , Preescolar , Infecciones Comunitarias Adquiridas/diagnóstico por imagen , Infecciones Comunitarias Adquiridas/microbiología , Endocarditis Bacteriana/diagnóstico por imagen , Corazón/anatomía & histología , Humanos , Masculino , Infecciones Estafilocócicas/diagnóstico por imagen , UltrasonografíaRESUMEN
No disponible
Asunto(s)
Humanos , Masculino , Preescolar , Endocarditis Bacteriana/complicaciones , Endocarditis Bacteriana/diagnóstico , Endocarditis Bacteriana/tratamiento farmacológico , Staphylococcus aureus/aislamiento & purificación , Meticilina/uso terapéutico , Resistencia a la Meticilina , Staphylococcus aureus Resistente a Meticilina/aislamiento & purificación , Endocarditis BacterianaRESUMEN
A 15 year-old male adolescent was hospitalized in a severe septic condition, due to infectious endocarditis which abided for 20 days. The admittance echocardiogram displayed a mitral valve vegetation in conjunction to a hypertrophic cardiomyopathy. In spite of applied antibiotics the patient expired. The authors emphasize the diagnostic difficulties of this compound entity and stress the need of antibiotic prophylaxis for patients who bear a hypertrophic cardiomyopathy, even in those with a non-obstructive disposition
Asunto(s)
Humanos , Masculino , Adolescente , Cardiomiopatía Hipertrófica/complicaciones , Endocarditis Bacteriana/complicaciones , Infecciones Estreptocócicas/complicaciones , Cardiomiopatía Hipertrófica , Ecocardiografía , Endocarditis Bacteriana , Infecciones EstreptocócicasRESUMEN
Marfan's syndrome is an inherited disorder of the connective tissue. Cardiologic manifestations, especially aortic dilation, are important causes of morbidity and mortality in the clinical course of the disease in adults and teenagers. In children, the presence of aortic aneurysm and its dissection or rupture is rare, occurring in patients with genetic mutation of the fibrillin gene but not in those who have the familial form of the disease. We describe here 2 patients, from the same family (siblings), diagnosed with gigantic aortic aneurysm early in infancy, one of them successfully undergoing surgery
Asunto(s)
Humanos , Masculino , Femenino , Niño , Aneurisma de la Aorta , Síndrome de Marfan/diagnóstico , Aneurisma de la Aorta , Síndrome de Marfan/fisiopatología , Síndrome de Marfan/cirugíaRESUMEN
OBJECTIVE: Noninvasive cardiac assessment of newborns and infants of women with systemic lupus erythematosus. The children had no congenital total atrioventricular block and were compared with the children of healthy women. METHODS: We prospectively assessed 13 newborns and infants aged 1 to 60 days, children of women with systemic lupus erythematosus and without congenital total atrioventricular block. These children were compared with 30 children of women who had no lupus or anti-Ro/SSA antibodies, and no risk factors for congenital heart disease either. Their age groups matched. The following examinations were performed: cardiological physical examination, electrocardiography, echocardiography, and signal-averaged electrocardiography. RESULTS: The statistical analysis showed no significant difference in ventricular function or in the cardiac conduction system between the groups. CONCLUSION: In regard to the conduction system and ventricular function in the absence of total atrioventricular block, no statistically significant difference was observed between the children of women with systemic lupus erythematosus and children of healthy women