RESUMEN
We evaluated the in vitro and in vivo effects of an XeCl excimer laser on the eyelid and anterior segments of the eye. The wavelength of this laser was successfully transmitted through a quartz fiberoptic system. The action of the XeCl excimer laser through our system was more photocoagulative than photoablative.
Asunto(s)
Segmento Anterior del Ojo/efectos de la radiación , Párpados/efectos de la radiación , Rayos Láser/métodos , Animales , Segmento Anterior del Ojo/ultraestructura , Córnea/efectos de la radiación , Epitelio/efectos de la radiación , Párpados/ultraestructura , Iris/efectos de la radiación , Microscopía Electrónica de Rastreo , Conejos , Porcinos , XenónRESUMEN
The possible competition of isoniazid for the acetylation of sulphadimidine was studied by comparing the degree of acetylation of urine sulphadimidine (1 g orally) in isoniazid-treated and in isoniazid-untreated patients. The former group (isoniazid 300 mg once daily) consisted of 5 slow and 5 rapid acetylators and the latter group of 5 and 6 respective acetylator phenotypes. In all of the 4-8, 8-12 and 12-24 h urine fractions, the acetylation percentage of sulphadimidine and its distribution pattern were practically unaffected by the isoniazid. This suggests that isoniazid therapy does not interfere significantly with the routine acetylator phenotyping by means of sulphadimidine.