RESUMEN
Two sisters aged 12 and 13 applied to our hospital with complaints of jerking tonic contraction triggered by sudden noise. Diffuse bilaterally polyspike-wave discharges appeared on waking electroencephalography and during that time a startle-induced tonic contraction was seen. Their neurological examinations and neuro-radiological imaging were normal except for hyperreflexia. We presented these cases because of being rare.
Asunto(s)
Aberraciones Cromosómicas/genética , Genes Dominantes/genética , Rigidez Muscular/genética , Reflejo Anormal/genética , Reflejo de Sobresalto/genética , Estimulación Acústica , Adolescente , Niño , Trastornos de los Cromosomas , Electroencefalografía , Femenino , Humanos , Rigidez Muscular/diagnóstico , FenotipoRESUMEN
This study was performed to investigate the serum and hair zinc levels in patients epilepsy diagnoses who were intended to be put on valproic acid (VA) monotherapy and had never ingested antiepileptics before. A total of 16 patients having normal growth, development and nutrition was selected as Group 1, and Group 2 was made up of 10 patients who had received VA monotherapy for 2 yrs or more and had normal growth, development, and nutrition characteristics. A control group (Group 3) was formed of 15 subjects who applied to the hospital for upper respiratory tract disorders. Serum and hair samples were taken for zinc assays from the Group 1 patients on the d 0, 15, 30, 45, 60, 75, and 180. Groups 2 and 3 were sampled only once, and zinc levels were determined. We found that both serum and hair zinc levels in Group 1 were higher than those of Group 2 and control group before the beginning of VA therapy, but they returned to normal during VA treatment. There was no zinc deficiency, and zinc replacement treatment may therefore be considered as unnecessary.
Asunto(s)
Anticonvulsivantes/uso terapéutico , Epilepsia/metabolismo , Cabello/química , Ácido Valproico/uso terapéutico , Zinc/análisis , Adolescente , Niño , Preescolar , Epilepsia/sangre , Epilepsia/tratamiento farmacológico , Femenino , Humanos , Lactante , Masculino , Zinc/sangreRESUMEN
A case of Aicardi's syndrome is described. The main features described are infantile spasms, pathognomonic chorioretinal lacunar defects, agenesis of the corpus callosum, psychomotor retardation, female sex, characteristic EEG changes and costovertebral anomalies. This is the second reported case in Turkey.
Asunto(s)
Agenesia del Cuerpo Calloso , Enfermedades de la Coroides/diagnóstico , Trastornos Psicomotores/diagnóstico , Enfermedades de la Retina/diagnóstico , Espasmos Infantiles/diagnóstico , Electroencefalografía , Femenino , Humanos , Lactante , Factores Sexuales , SíndromeRESUMEN
Not all patients with tuberculosis develop tuberculoma during the disease or antituberculous therapy. Therefore, we compared various parameters in patients with and without tuberculoma and presented the results. We formed two groups from the patients with tuberculous meningitis: Group I consisted of 18 patients with tuberculoma, and Group II consisted of 18 randomly selected patients without tuberculoma. Significant difference between the groups was found with respect to level of consciousness and CSF-glucose level (p < 0.05). The consciousness level was more depressed and the CSF-glucose level more decreased in the group without tuberculoma. These findings were discussed.
Asunto(s)
Tuberculoma Intracraneal/etiología , Tuberculosis Meníngea/complicaciones , Estudios de Casos y Controles , Distribución de Chi-Cuadrado , Niño , Estado de Conciencia , Glucosa/líquido cefalorraquídeo , Humanos , Pronóstico , Radiografía , Tuberculoma Intracraneal/líquido cefalorraquídeo , Tuberculoma Intracraneal/diagnóstico por imagen , Tuberculosis Meníngea/líquido cefalorraquídeo , Tuberculosis Meníngea/diagnóstico por imagenAsunto(s)
Amoníaco/sangre , Anticonvulsivantes/efectos adversos , Epilepsia/tratamiento farmacológico , Ácido Valproico/efectos adversos , Adolescente , Adulto , Amoníaco/análisis , Anticonvulsivantes/sangre , Carnitina/uso terapéutico , Niño , Preescolar , Femenino , Humanos , Lactante , Hepatopatías/complicaciones , Masculino , Ácido Valproico/sangreRESUMEN
We report a brother and a sister with Vogt-Koyanagi-Harada syndrome. The girl had all the manifestations of this condition; her brother was less severely affected. Both showed mental and growth retardation. The literature on this syndrome is reviewed.
Asunto(s)
Trastornos de la Audición/genética , Meningoencefalitis/genética , Uveítis/genética , Vitíligo/genética , Anomalías Múltiples/genética , Adolescente , Niño , Femenino , Trastornos del Crecimiento/complicaciones , Trastornos del Crecimiento/genética , Cabello/anomalías , Trastornos de la Audición/complicaciones , Humanos , Discapacidad Intelectual/complicaciones , Discapacidad Intelectual/genética , Masculino , Meningoencefalitis/complicaciones , Linaje , Síndrome , Uveítis/complicaciones , Vitíligo/complicacionesRESUMEN
Between May 1988 and November 1992 the data from 52 patients with tuberculous meningitis (TBM) were noted down for their symptoms and signs, BCG vaccines, PPD tests; clinical, laboratory, radiologic and microbiologic findings. These data were discussed by means of literature knowledge. Cranial computed tomography (CT) demonstrated hydrocephalus (HC) in 98% of the patients. There was a statistically significant difference among the clinical stages on admission in respect to prognosis (P < 0.05). In addition, there was also a significant relationship between prognosis and HC (P < 0.05). However, we did not find any significant relationship between parenchymal involvement, basilar meningitis and prognosis (P > 0.05).
Asunto(s)
Tuberculosis Meníngea , Adolescente , Encéfalo/diagnóstico por imagen , Niño , Preescolar , Femenino , Humanos , Hidrocefalia/complicaciones , Lactante , Masculino , Pronóstico , Tomografía Computarizada por Rayos X , Tuberculosis Meníngea/complicaciones , Tuberculosis Meníngea/diagnóstico por imagen , Tuberculosis Meníngea/patologíaRESUMEN
A patient is reported with a suprasellar tuberculoma which imitated a craniopharyngioma on computed tomography scan and magnetic resonance imaging of the brain. This lesion developed during irregularly used antituberculous therapy and caused endocrinologic disorders 3 years after the original diagnosis of tuberculous meningitis. Surgery was performed to confirm the diagnosis and also to decompress the optic pathways. Five months later, the lesion disappeared completely after appropriate antituberculous treatment.