RESUMEN
The Davidson and Hemmendinger (DH) color rule was evaluated for color vision screening of normal and congenital color-defective subjects. Ninety-eight normal and 14 color-defective subjects were tested on the color rule under Macbeth illumination of 5,400 K. The color-defective subjects were also tested on the Nagel anomaloscope, the Farnsworth D-15, and the H-R-R pseudoisochromatic plates. The DH color rule performed as accurately as the anomaloscope and was superior to the other two tests in detecting anomalous trichromats and in discriminating protanomalous subjects. The color rule also discriminated dichromats from anomalous trichromats. For severe color-defective subjects (dichromats, achromats), the color rule was more time-consuming than the other tests and discrimination was less certain. Response patterns on the DH color rule and response variability of the different classifications are reported.
Asunto(s)
Pruebas de Percepción de Colores/métodos , Defectos de la Visión Cromática/diagnóstico , Adolescente , Adulto , Niño , Pruebas de Percepción de Colores/instrumentación , Humanos , Iluminación , Persona de Mediana EdadRESUMEN
Blue cone monochromatism (BCM) is a subtype of achromatopsia in which the blue cone mechanism predominates. Each of the four patients in this study had BCM proven by their having peak spectral sensitivities in the blue region of the visible spectrum (near 440 nm). Clinically, the diagnosis was suspected because of x-linked inheritance, the presence of acuities better than 20/200 in two patients and myopia ranging from -1.75 to -15.00 diopters in three patients. Congenital nystagmus was the presenting sign in three of the four patients. Examination of the fundi was uniformly normal. The distinctive spectral properties of BCM were demonstrated by the American Optical H-R-R and the Panel D-15 tests. All affected patients correctly identified three of the four blue-yellow plates and a variable number of the red-green plates in the American Optical H-R-R test. The study patients consistently made errors oriented along the protan and deutan axes but they made none along the tritan axis. The authors conclude that the results of these two color discrimination tests are useful in diagnosing BCM.
Asunto(s)
Células Fotorreceptoras/anomalías , Enfermedades de la Retina/congénito , Niño , Pruebas de Percepción de Colores , Electrorretinografía , Estudios de Evaluación como Asunto , Humanos , Masculino , Nistagmo Patológico/congénito , Linaje , Estimulación Luminosa , Enfermedades de la Retina/diagnóstico , Enfermedades de la Retina/genética , Pruebas de Visión , Agudeza VisualAsunto(s)
Electrorretinografía , Oftalmopatías/diagnóstico , Mácula Lútea , Adaptación Ocular , Oftalmopatías/fisiopatología , Humanos , Luz , Mácula Lútea/fisiología , Mácula Lútea/fisiopatología , Oftalmoscopía , Nervio Óptico/fisiología , Nervio Óptico/fisiopatología , Retina/fisiología , Retina/fisiopatología , Escotoma/diagnósticoAsunto(s)
Adaptación Ocular , Oscuridad , Electrorretinografía , Retina/fisiología , Percepción de Color , Adaptación a la Oscuridad , Femenino , Humanos , Reflejo , Factores de TiempoAsunto(s)
Complicaciones de la Diabetes , Retinopatía Diabética/diagnóstico , Electrooculografía , Electrorretinografía , Potenciales Evocados Visuales , Oftalmopatías/diagnóstico , Catarata/diagnóstico , Retinopatía Diabética/complicaciones , Diagnóstico Diferencial , Hemorragia/diagnóstico , Humanos , Pronóstico , Desprendimiento de Retina/diagnóstico , Cuerpo VítreoAsunto(s)
Percepción de Distancia , Movimientos Oculares , Percepción del Tamaño , Adaptación Ocular , Adulto , Fijación Ocular , HumanosRESUMEN
The historical development of the foveal electroretinogram is reviewed. The factors required to obtain a local cone electroretinogram with a small focal source of illumination against a lighted background are discussed. From these considerations and various studies of macular degeneration, the optimal size of the foveal source is found to be 5 degrees diameter or less. Applications of the foveal electroretinogram in various diseases are summarized. The foveal electroretinogram is abnormal with reduced acuity in age-related macular degeneration, juvenile macular degeneration (Stargardt's disease), retinitis pigmentosa, and diabetic retinopathy. Normal foveal electroretinograms are found in optic atrophy, amblyopia, and optic neuritis. Foveal electroretinograms are normal or abnormal in Best's disease, central serous retinopathy, and several other diseases discussed.
Asunto(s)
Electrorretinografía , Fóvea Central/fisiopatología , Mácula Lútea/fisiopatología , Envejecimiento , Electrorretinografía/métodos , Humanos , Degeneración Macular/diagnóstico , Degeneración Macular/fisiopatología , Enfermedades del Nervio Óptico/diagnóstico , Enfermedades del Nervio Óptico/fisiopatología , Enfermedades de la Retina/diagnóstico , Enfermedades de la Retina/fisiopatología , Agudeza VisualRESUMEN
Visual evoked potentials were recorded monopolarly from seven electrodes on a horizontal line from T3 to T4 and bipolarly in one channel from left of the midline to right of the midline. Stimulation of the right and left half-fields was performed with a checkerboard generator of 10 degrees x 13.5 degrees and checks of various sizes at high contrast. The results may be summarized as follows: 1. Source-sink analysis for lateral half-field pattern onset with small checks shows C1, peaking about 80 msec, to have a source on the scalp contralateral to the half-field stimulated with a sink on the midline. 2. To half-field pattern reversal, bipolar recording across the scalp midline indicates an early phase reversal peaking about 80 msec followed by another phase reversal peaking at about P100 latency. Source-sink analysis indicates the first reversal has a contralateral source, while the second has a source on the scalp midline or ipsilateral to the field stimulated. 3. Pattern reversal results vary with check size, with a smaller check size increasing the amplitude of the first phase reversal and decreasing the amplitude of the second.
Asunto(s)
Potenciales Evocados Visuales , Cuero Cabelludo/fisiología , Humanos , Estimulación Luminosa/métodos , Tiempo de ReacciónRESUMEN
Congenital nystagmus (CN) is a common disorder indicative of a primary disturbance of the ocular motor or visual sensory systems. The authors prospectively evaluated 81 patients with CN, structurally normal eyes, and minimal or no abnormalities of the optic nerve, macula, and retinal pigment epithelium (RPE). Seventy-four (91%) patients were found to have a disorder of the visual sensory system. Thirty-four patients had albinism, 37 had a congenital or early onset disorder of the retinal photoreceptors, and 3 had abnormalities of the optic nerve. The remaining seven (9%) patients had motor CN. Most patients presenting with CN have visual loss and should be evaluated for an underlying disorder of the visual sensory system.
Asunto(s)
Nistagmo Patológico/congénito , Trastornos de la Visión/etiología , Adolescente , Adulto , Factores de Edad , Albinismo/complicaciones , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Enfermedades del Nervio Óptico/complicaciones , Degeneración Retiniana/complicaciones , Estudios Retrospectivos , Agudeza VisualRESUMEN
Visual evoked potentials from seven horizontally spaced electrodes were recorded from normal subjects and subjects with homonymous hemianopia in response to hemifield pattern flash stimulation. Stimulation produced a large early peak that was positive on the scalp contralateral to the hemifield and negative on the ipsilateral scalp. From computer fitting of the amplitudes versus electrode position, the position of the equivalent source was found to be in the contralateral hemisphere. The horizontal orientation of the dipole source was approximately tangential (parallel) to the occipital scalp surface with negative polarity toward the medial fissure. In normal subjects, visual evoked potential amplitudes at the first peak were positive on the left and negative on the right for right hemifield stimulation. Left hemifield stimulation showed the opposite results. Three patients with homonymous hemianopia showed normal visual evoked potential results from their functional hemifields and nearly flat results from their hemianopic hemifields. The normal visual evoked potentials originated in their intact cortical hemispheres.
Asunto(s)
Potenciales Evocados Visuales , Hemianopsia/fisiopatología , Reconocimiento Visual de Modelos , Adulto , Electrodos , Humanos , Masculino , Persona de Mediana Edad , Estimulación Luminosa , Agudeza Visual , Campos VisualesRESUMEN
Photopic, 30-Hz, and foveal electroretinograms were measured in 19 diabetic patients in an experimental study of the effects of short-term Sorbinil (an aldose-reductase inhibitor) on retinal function. Patients were assigned in double-blind fashion to Sorbinil (250 mg/day) or placebo groups and were tested at the outset and after four weeks of therapy. Comparisons (t-test) between the Sorbinil and placebo groups failed to show significant effects of treatment on electroretinograms, although there was a significant correlation within the Sorbinil group between foveal recordings and red cell sorbitol at the end of treatment. Analysis showed that increased foveal electroretinograms were found in patients with low initial retinopathy but not in those with greater retinopathy. Eight patients continued Sorbinil treatment for one year. Again patients improving their foveal measurements had less initial retinopathy than those not improving. This difference was significant after one year of treatment but not at four weeks.