[Effect of extra- and intra-cranial vascular anastomosis on regional blood flow, studied by SPECT using 99m-Tc HMPAO]. / Extra-intracraniális éranastomosis mütét regionális agyi vérátáramlásra gyakorolt hatásának vizsgálata 99mTc-HMPAO agyi SPECT-tel.

Thirty-two patients suffering from occlusive cerebrovascular disease were investigated by means of 99mTc-HMPAO brain SPECT before and one month after EC-IC bypass operation. The regional cerebral blood flow was unchanged postoperatively in 19 patients, increased in 7 cases, and deteriorated in 6 patients. One patient died in the postoperative period and in another no follow-up SPECT could be performed. It is concluded that the regional cerebral blood flow, even in the absence of a morphological deficit on CT, was not improved by the operation in the majority of cases.

[Regional cerebral blood flow studied by single photon emission computed tomography (SPECT)]. / Regionális agyi vérátfolyás vizsgálata egyfotonos emissiós computer tomographiával (SPECT).

Clinical experience based on regional cerebral blood flow investigations with 99mTc HMPAO SPECT in 164 patients is reported. The pharmacokinetics of the 99mTc HMPAO are summarised, and the important indications of the investigations are interpreted in case reports (stroke, surgical solution of intracavernous aneurysm, Alzheimer and multiinfarct types of dementias). The literature data suggest that the diagnostic possibilities with this method are good in other diseases too, this area is surveyed briefly.